The Sicarii were a self-defense splinter group of Hebrew zealots who opposed the Roman occupation of Judea in the decades preceding the destruction of Jerusalem in 70 CE.
Sicarius, sicarii or sicari may also refer to:
- Sicarii (1989), a Jewish terrorist group in Israel
- Sikrikim, or Sicarii, members of an ultra-orthodox modern Israeli sect
- Sicaricon, the Roman-era laws concerning the usurping occupant of lands in Judea
- Saint Sicarius or Sicharius, name of several Christian saints
- Sicarius of Brantôme, Christian child saint
- Sicarius (spider), a genus of venomous spiders belonging to the family Sicariidae
- Vincenza Sicari (born 1979), Italian long-distance runner