Siege of Rome may refer to:
- Siege of Rome (508 BC), by Clusium
- Siege of Rome (408), see Sack of Rome (410)
- Siege of Rome (409), see Sack of Rome (410)
- Siege of Rome (472), by Ricimer
- Siege of Rome (537–538), by the Ostrogoths
- Siege of Rome (546), by the Ostrogoths
- Siege of Rome (549–550), by the Ostrogoths
- Siege of Rome (756), by the Lombards under Aistulf
- Siege of Rome (1082–1084), by Henry IV, Holy Roman Emperor
- Siege of Rome (1849), by the French
See also
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- Arab raid against Rome (846)
- Capture of Rome (1870), by the Kingdom of Italy
- Liberation of Rome (1944), by the Allies during World War II
- Fall of Rome (disambiguation)
- Sack of Rome (disambiguation)
- Battle of Rome (disambiguation)
- Battle for Rome (disambiguation)