Smith Family may refer to:
- Smith family (Latter Day Saints), American family with many members prominent in religion and politics
- Smith family (Sierra Leone), Creole family of Sierra Leone
- Smith family (bankers), English banking family founded by Thomas Smith (1631–1699)
- The Smith Family (charity), Australian, independent non-profit children's charity
- The Smith Family (TV series) (1971–1972), American television series, starring Henry Fonda
- Smith family, fictional family of American Dad!
- Smith family, fictional family of EastEnders, introduced in 1985 with Mary Smith
- Smith family, fictional family of EastEnders, introduced in 2002 with Gus Smith
- Smith family, fictional family of Rick and Morty