Smithereens means 'tiny pieces'. It may also refer to:
- Natives of Smithers, a town in Canada.
- General Sir Horace Smith-Dorrien (1858–1930), being one of his nicknames.
- Smithereens (book) a 2004 book by Shaun Micallef.
- Smithereens (film), a 1982 film by Susan Seidelman.
- Smithereens, a 1998 album by Nick Harper, or its title track.
- Smithereens, a 2005 album by Elin Sigvardsson.
- "Smithereens", a 2018 song by Twenty One Pilots from the album Trench.
- Smithereens, a 2022 album by Joji.
- "Smithereens", an episode of British science fiction television series Black Mirror.
- Smithereens!, a 1982 game for the Magnavox Odyssey² console.
- The Smithereens, a rock band from New Jersey.