The spinomesencephalic pathway, spinomesencephalic tract or spino-quadrigeminal system of Mott, includes a number of ascending tracts in the spinal cord, including the spinotectal tract.[1][2][3] The spinomesencephalic tract is one of the ascending tracts in the anterolateral system of the spinal cord that projects to various parts of the midbrain.[1] It is involved in the processing of pain and visceral sensations.[4]
Spinomesencephalic pathway | |
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Anatomical terminology |
In the ALS
editThe anterolateral system (ALS) is a bundle of afferent somatosensory fibers from different ascending tracts in the spinal cord. These fibers include those of the spinomesencephalic tract, spinothalamic tract, and spinoreticular tract amongst others.[5] Spinomesencephalic fibres project to the periaqueductal gray, and to the tectum. Other fibers project to and terminate in the parabrachial nucleus, the pretectum, and the nucleus of Darkschewitsch.[1] The fibers that project to the tectum are known as the spinotectal fibers.[5] The spinotectal tract fibers project to the superior colliculus. Where they synapse onto cells of the deeper superior colliculus they are activated by noxious stimuli.[1]
Anatomy
editThe spinomesencephalic tract consists mostly of myelinated fibers. The neurons are either low-threshold of a wide dynamic range, or high threshold,[1] with many of the cells being nociceptive.[1]
Origin
editCells of the spinomesencephalic tract arise mostly in Rexed lamina I, and to a lesser extent in Rexed laminae IV and VI-VIII) of the spinal cord. They are mostly concentrated in lamina V.[1] The tract is in the same region as the spinothalamic tract.[1]
Course
editMost of the spinomesencephalic fibers decussate to ascend contralaterally, but there is a noted group of uncrossed fibers in the upper cervical levels.[1]
See also
editReferences
edit- ^ a b c d e f g h i Standring, Susan (2016). Gray's anatomy: the anatomical basis of clinical practice . Digital version (41st. ed.). Philadelphia, Pa.: Elsevier. p. 433. ISBN 9780702052309.
- ^ Patestas, Maria A.; Gartner, Leslie P. (2016). A Textbook of Neuroanatomy (2nd ed.). Hoboken, New Jersey: Wiley-Blackwell. pp. 112, 203–204, 224–225. ISBN 978-1-118-67746-9.
- ^ Gray, Henry (1918). Gray's Anatomy (20th ed.). p. 762.
- ^ Kiernan, John A.; Rajakumar, Nagalingam (2013). Barr's The Human Nervous System: An Anatomical Viewpoint (10th ed.). Philadelphia: Wolters Kluwer Lippincott Williams & Wilkins. p. 74. ISBN 978-1-4511-7327-7.
- ^ a b Haines, Duane (2018). Fundamental neuroscience for basic and clinical applications (Fifth ed.). Philadelphia, PA: Elsevier. p. 259. ISBN 9780323396325.