Borrelia duttoni (formerly known as Spirochaeta duttoni)[1] is a species of Borrelia.[2] It is the endemic causative agent of tick-borne relapsing fever in parts of sub-Saharan Africa, and Madagascar. It is transmitted by the soft-bodied tick Ornithodoros moubata which sheds the pathogen in its saliva and coxal fluid. Vertical transmission occurs in ticks which thus appear to represent the major reservoir of this pathogen. Humans appear to be the sole vertebrate host of B. duttoni, although chickens and pigs may be infected according to research performed in East Africa.[3][4] Human disease is characterised by a long incubation period, numerous brief recurrences, and frequent ocular involvement. Infection results immunity which is enduring but strain-specific.[5]
| Borrelia duttoni | |
|---|---|
Scientific classification 
| |
| Domain: | Bacteria |
| Phylum: | Spirochaetota |
| Class: | Spirochaetia |
| Order: | Spirochaetales |
| Family: | Borreliaceae |
| Genus: | Borrelia |
| Species: | B. duttoni
|
| Binomial name | |
| Borrelia duttoni (Novy and Knapp 1906) Bergey et al. 1925 (Approved Lists 1980)
| |
It is named after Joseph Everett Dutton, who died of the disease in 1905 while he and John Lancelot Todd were investigating "tick fever".[6]
References
edit- ^ Garnham, P. C. (1974). "Edward Hindle, 1886-1973". Biographical Memoirs of Fellows of the Royal Society. 20: 217–234. doi:10.1098/rsbm.1974.0009. PMID 11615757. S2CID 40996516.
- ^ Vial L, Durand P, Arnathau C, et al. (September 2006). "Molecular divergences of the Ornithodoros sonrai soft tick species, a vector of human relapsing fever in West Africa". Microbes Infect. 8 (11): 2605–11. doi:10.1016/j.micinf.2006.07.012. PMID 16962358.
- ^ Service, Mike (2012). Medical Entomology for Students (Fifth ed.). Cambridge University Press. p. 233. ISBN 978-1-107-66818-8.
- ^ McCall, P.J.; Hume, Jen C.C.; Motshegwa, Kefentse; Pignatelli, Patricia; Talbert, Alison; Kisinza, William (2007). "Does Tick-Borne Relapsing Fever Have an Animal Reservoir in East Africa?". Vector-Borne and Zoonotic Diseases. 7 (4): 659–666. doi:10.1089/vbz.2007.0151. PMID 18021022.
- ^ "Dictionnaire médical de l'Académie de Médecine". www.academie-medecine.fr. Retrieved 2024-02-15.
- ^ Cook, Gordon (2007-09-17). Tropical Medicine: An Illustrated History of The Pioneers. Academic Press. pp. 167–169. ISBN 978-0-08-055939-1. Retrieved 2013-05-08.
 | This Spirochaete-related article is a stub. You can help Wikipedia by expanding it. |