Sulfacytine

Sulfacytine
Clinical data
Other names	1-ethyl N4-sulfanilylcytosin, 1-ethyl-N-sulfanilylcytosine, N-sulfanilyl-l-ethylcytosine, Sulfacitina [inn-spanish], Sulfacitinum [inn-latin]
Routes of; administration	Oral
Identifiers
	IUPAC name 4-amino-N-(1-ethyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzene-1-sulfonamide;
CAS Number	17784-12-2;
PubChem CID	5322;
PubChem SID	46505483;
DrugBank	DB01298;
ChemSpider	5131;
UNII	T795873AJP;
ChEMBL	ChEMBL1201056;
CompTox Dashboard (EPA)	DTXSID6023606 ;
Chemical and physical data
Formula	C12H14N4O3S
Molar mass	294.33 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCN1C=CC(NS(=O)(=O)C2=CC=C(N)C=C2)=NC1=O;
	InChI InChI=InChI=1S/C12H14N4O3S/c1-2-16-8-7-11(14-12(16)17)15-20(18,19)10-5-3-9(13)4-6-10/h3-8H,2,13H2,1H3,(H,14,15,17); Key:SIBQAECNSSQUOD-UHFFFAOYSA-N;

Sulfacytine is a short-acting sulfonamide antibiotic, taken orally for treatment against bacterial infections. Sulfonamides, as a group of antibiotics, work by inhibiting the bacterial synthesis of folate.^[1] In 2006 the drug was discontinued^[2]^[3]

References

^ DrugBank DB01298
^ Federal Register Section: Food and Drug Administration [Docket No. 2006N–0222] Merck & Co., Inc., et al.; Withdrawal of Approval of 65 New Drug Applications and 52 Abbreviated New Drug Applications] Vol. 71, No. 116 / Friday, June 16, 2006. p34941
^ FDA Orange book. Sulfacytine Page accessed May 12, 2015

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[DrugBank-1] DrugBank DB01298

[2] Federal Register Section: Food and Drug Administration [Docket No. 2006N–0222] Merck & Co., Inc., et al.; Withdrawal of Approval of 65 New Drug Applications and 52 Abbreviated New Drug Applications] Vol. 71, No. 116 / Friday, June 16, 2006. p34941

[3] FDA Orange book. Sulfacytine Page accessed May 12, 2015

[1]

[2]

[3]

Clinical data

Other names	1-ethyl N4-sulfanilylcytosin, 1-ethyl-N-sulfanilylcytosine, N-sulfanilyl-l-ethylcytosine, Sulfacitina [inn-spanish], Sulfacitinum [inn-latin]
Routes of administration	Oral
Identifiers
IUPAC name 4-amino-N-(1-ethyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzene-1-sulfonamide
CAS Number	17784-12-2
PubChem CID	5322
PubChem SID	46505483
DrugBank	DB01298
ChemSpider	5131
UNII	T795873AJP
ChEMBL	ChEMBL1201056
CompTox Dashboard (EPA)	DTXSID6023606
Chemical and physical data
Formula	C₁₂H₁₄N₄O₃S
Molar mass	294.33 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCN1C=CC(NS(=O)(=O)C2=CC=C(N)C=C2)=NC1=O
InChI InChI=InChI=1S/C12H14N4O3S/c1-2-16-8-7-11(14-12(16)17)15-20(18,19)10-5-3-9(13)4-6-10/h3-8H,2,13H2,1H3,(H,14,15,17) Key:SIBQAECNSSQUOD-UHFFFAOYSA-N