TXN may refer to:
- TXN (gene), a gene encoding Thioredoxin
- Tarangan language (ISO 639:txn), spoken by inhabitants of the Aru Islands in eastern Indonesia
- Texas Instruments (NASDAQ: TXN)
- Texas Network, a media company
- Texas & New Mexico Railway (reporting mark: TXN)
- The Experts Network, an interactive digital sports network
- TX Network, Japan
- Huangshan Tunxi International Airport (IATA: TXN), China
- TXN, abbreviation for transaction (disambiguation)
- TXN, abbreviation for transcription (genetics)
- txn, abbreviation for Database transaction