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There have been articles published that have related hirano bodies to Alzheimer's disease; and, I think it I could update this page with how hirano bodies actually are associated to Alzheimer's disease. It would give hirano bodies more importance. It would also be more information about hirano bodies that could be useful to give the reader more of an idea in how they are relevant. Possible sources to start with-

1. A. Hirano, Hirano bodies and related neuronal inclusions. Neuropathol. Appl. Neurobiol. 20, 3-11 (1994).
2. A. Hirano, H. Zimmerman, Alzheimer's neurofibrillary changes: a topographic study. Arch. Neurol. 7, 227-242 (1962).
3. S. Mitake, K. Ojika, A. Hirano, Hirano bodies and Alzheimer's disease. Kaohsiung J. Med. Sci. 13, 10-18 (1997).
4. D. P. Perl, Neuropathology of Alzheimer's disease. Mt. Sinai J. Med. 77, 32-42 (2010).
Kdgaffney (talk) 02:51, 1 October 2016 (UTC)Reply


"Hirano bodies are cytoplasmic protein aggregates of actin and actin associated proteins that affect the cytoskeletal structure of nerve cells. They are elongated, glassy, eosinophilic bodies consisting of paracrystalline arrays of beaded filaments. The are found most commonly in hippocampal pyramidal cells. They have been associated with neurodegenerative diseases such as Alzheimer's disease."

haha, this is straight out of robbin's pathology,

True, thanks for pointing this out. I've reworded the stub & added Robbins as a reference. -RustavoTalk/Contribs 05:01, 20 May 2007 (UTC)Reply

Wiki Education Foundation-supported course assignment

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  This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Kdgaffney. Peer reviewers: Mejoh004, Gicoo001.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 09:58, 18 January 2022 (UTC)Reply