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While
editWhile I haven't researched IL-10 in any fashion since 1998, I believe that the cytokines that are inhibited by IL-10 on CD4+ T cells depended upon the species: IL-10 inhibits both Th1 and Th2 cytokines in human T cells (although there was debate as to whether there was a larger inhibition of Th1 cytokines), whereas it only significantly inhibited Th1 cytokines in mice.
Also, I believe that IL-10 could also facilitate antibody class switching in B cells, but that wasn't near my area of research. I don't have the references on me, but I can dig them up if someone wants more detail. Volantares 08:19, 23 August 2005 (UTC)
- Please do. Your expertise is welcomed, and 7 yr old info is better than no info at all! JFW | T@lk 12:02, 23 August 2005 (UTC)
Wow guys, this info's nine year's old now. But rest assured, at a brief glance, the information's correct. However, with regard to what Volantares said above, IL-10 not just inhibits Th1 cytokine secretion, it inhibits the cells all together, contributing to Th2 prevailance. Diuness —Preceding signed but undated comment was added at 03:46, 5 October 2007 (UTC)
Typo
editCounteracting is misspelled ("couteracting") in the intro, but I can't seem to edit the top section, only the title and then the function section. Someone who is more skilled at editing should do that if they get the chance. —Preceding unsigned comment added by 129.112.109.250 (talk) 21:33, 28 July 2008 (UTC)
- Fixed! Used the edit page link at the top of the page to access the paragraph. ~ Ciar ~ (Talk to me!) 23:30, 28 July 2008 (UTC)