Talk:Ipratropium bromide

Atrovent nasal spray

This article should probably also mention the drug's use as a nasal spray (for treatment of runny nose from various medical conditions). Richwales 22:53, 30 November 2007 (UTC)

The exact same medication is supplied as either a nasal spray or an inhalant. Information can be found at this page on the internet drug index.1archie99 (talk) 13:10, 14 August 2011 (UTC)

The internet drug index page doesn't work anymore.

--ee1518 (talk) 11:22, 14 October 2020 (UTC)

Ipratropium blocks M2 mAChR receptors ?

Someone else left this comment in the introduction to the article. Since it does not belong inside the article, I moved it here: "I swear this said Ipratropium blocked M2 mAChR receptors when I last checked." Liawagner (talk) 03:27, 13 February 2010 (UTC)

Requested move

The following discussion is an archived discussion of a requested move. Please do not modify it. Subsequent comments should be made in a new section on the talk page. No further edits should be made to this section.

The result of the move request was: move. Graeme Bartlett (talk) 05:46, 13 March 2011 (UTC) Graeme Bartlett (talk) 05:46, 13 March 2011 (UTC)

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Ipratropium → Ipratropium bromide —

• This is the full name of the drug described in the article. See references in article. This would require elimination of the redirect page. I suggest if a redirect is really required that the current article title be the title of the redirect page. Relisting Andrewa (talk) 12:02, 14 February 2011 (UTC) 1archie99 (talk) 16:35, 6 February 2011 (UTC)
• Comment there is no bromine in the compound... 64.229.101.119 (talk) 20:23, 6 February 2011 (UTC)
  • The cites discuss ipratropium bromide not ipratropium; the drug itself is what is notable, not what it is composed of.1archie99 (talk) 17:49, 11 February 2011 (UTC)

Relisting... there seems to be a great deal of confusion as to what the exact topic of this article is or should be, Both the schematic and the systematic name given in the infobox appear to contain no bromine, as stated above. The bromide, however, may well be the form used in some or even all pharmeceuticals. This needs to be sorted out. Andrewa (talk) 12:02, 14 February 2011 (UTC)

• Support per Wikipedia:WikiProject_Pharmacology/Style_guide#Drug_pages_to_use_INN. Ipratropiam bromide is the INN (see link, for example). In this case, since the active species is a cation, it cannot exist in any form except as a salt, and thus the INN includes "bromide" in the name. The drugbox data can be updated to include information on the bromide. -- Ed (Edgar181) 14:33, 15 February 2011 (UTC)
  • Interesting point. The policy talks about the "INN of the active moiety" which is somewhat contradictory in this case. You are right, but I must admit I'm not particularly happy with this: We'll have to move Tiotropium, Ipratropium/salbutamol and possibly other pages. And what if a cation is marketed in different salt forms? As far as I know that's exactly why the policy wants us to use the names of active moieties. --ἀνυπόδητος (talk) 16:05, 15 February 2011 (UTC)
    • I seem to recall that this situation has been discussed somewhere before, but I can't find it at the moment. Probably it should be brought up at WT:PHARM. I'd be content with naming these types of articles either way, but we should at least be consistent. -- Ed (Edgar181) 16:32, 15 February 2011 (UTC)
      • It would be good to find the previous discussion, to save reinventing the wheel here.
      • In that the function of the INN is to uniquely and comprehensively identify a particular drug for practical purposes, does the WHO even distinguish between Ipratropium and Ipratropium bromide? There seems no reason for them to do so.
      • There are several other considerations that come to mind, but that's start. It's complicated. Andrewa (talk) 19:52, 15 February 2011 (UTC)
• Support per WHO guidance on International Nonproprietary Names (see WT:PHARM), which we really should enshrine in the style guide. Fvasconcellos (t·c) 16:57, 4 March 2011 (UTC)

The above discussion is preserved as an archive of a requested move. Please do not modify it. Subsequent comments should be made in a new section on this talk page. No further edits should be made to this section.

The name of the drug in the intro should be identfied as ipratropium bromide.

I believe that the name of the drug in the intro should be identfied as ipratropium bromide. I would prefer that someone with chemical expertise decide whether the word ipratropium alone has any place in this article.1archie99 (talk) 18:11, 11 February 2011 (UTC)

Well, I've a little knowledge (I studied chemistry up until the first year of a science degree, but dropped it partway through first year) and even that's enough to assure you that both the schematic and the systematic name given in the infobox can't possibly describe ipratropium bromide. But they might describe something called ipratropium, and it's my guess that they do.

Perhaps we should split the article. This article could remain focussed on the chemical compound ipratropium, but we split off an article on the pharmeceutical ipratropium bromide, and of course link the two. Andrewa (talk) 23:48, 14 February 2011 (UTC)

Oppose. The relevant policy is Wikipedia:WikiProject Pharmacology/Style guide#Drug pages to use INN where it says: If a compound exists in salt form, then the INN of the active moiety should be used. For example, "chlorphenamine maleate" is the INN modified (INNM) of a common first-generation antihistamine but only the chlorphenamine moiety is relevant for the antihistamine effect, thus its INN is used as the page title: Chlorphenamine. --ἀνυπόδητος (talk) 08:41, 15 February 2011 (UTC) See section above --ἀνυπόδητος (talk) 16:08, 15 February 2011 (UTC)

Pronounciation

I would like to know how to pronounce the name of this medication.1archie99 (talk) 13:15, 14 August 2011 (UTC)

Ipratropium and covid-19

"Some services and emergency departments have reported the use of ipratropium has made symptoms WORSE in covid-19. There is no concrete evidence one way or another".

https://www.emsworld.com/article/1224466/covid-19-symptoms-presentation-EMS

--ee1518 (talk) 11:47, 14 October 2020 (UTC)

Psychotropic effects.

I experienced mild hallucinations when I took two sprays in each nostril at night. It was a 0.03% solution prescribed for relief of bronchial obstruction. The effect was not unpleasant and I slept well with my CPAP machine loading air into my system. I also experienced a brief ‘lucid dream’ which is unusual and interesting. I briefly woke up, awakened by the sound of someone breathing with a CPAP machine operating. I experienced the sensation of being startled to find another person in bed with me (my Wife is out of town and I sleep alone). I patted the back and shoulders covered with a quilt and realized that it was me. I realized that I was outside my body and the room temperature is always cool. So I quickly returned to my body which was warm and comfortable. This was quite the experience and I attribute it to the nasal spray which is the only non-routine night-time med that I take.

I am experiencing none of the other side effects described in the literature and it works well with my other medicines. I may be contacted at elstun@icloud.com about this. 66.58.136.179 (talk) 17:54, 23 April 2022 (UTC)

pramlintide

https://www.rxlist.com/ipratropium/generic-drug.htm states that ipratropium in general can have a serious (but not "severe") interaction with pramlintide, a diabetes drug. The individual rxlist pages for the inhalant and nasal spray do not mention it. I checked webmd but they only identify classes of interaction drugs, not specific. Drugs.com interactions doesn't show ipratropium.

I've done a lot on this page in order to highlight the nasal spray, and I'm tired. I cited what I added. I'm not a pharma person so i didn't necessarily follow the hidden rules for wiki pharma, I just put stuff in next to each inhalant paragraph to address the nasal spray. The article intro lists side effects as well as a subsection, so I put it twice.

If somebody wants to find the proper fda or whatever source and do it right, I would be very grateful. Tkech (talk) 13:20, 22 March 2024 (UTC)