Talk:Levetiracetam

Wiki Education Foundation-supported course assignment

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Cvu28, Keppra28, Jzhang28, Druginfo28. Peer reviewers: Meghanw27, Kkyann27, Stephanie Truong Group 27, Aajeng27.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 02:30, 17 January 2022 (UTC)

Explanation of article edit of 22:09, 10 May 2007

The "care should not be taken to go over dosage" comment was related to the vitamin, and not Levetiracetam (but sounded like it was talking about Levetiracetam). — Preceding unsigned comment added by Wutudoin (talk • contribs) 22:10, 10 May 2007

dosage form

Keppra comes as a pill/tablet, generally. Is there an injectable form of Levetiracetam also? --98.70.132.83 (talk) 22:48, 2 June 2010 (UTC)

I should have done a little more google searching before asking the question... Here's the answer in case anyone else was wanting to know, also someone who's good with writing could add it to the article:

• 250 mg KEPPRA tablets are blue, oblong-shaped, scored, film-coated tablets marked with “ucb 250” on one side.
• 500 mg KEPPRA tablets are yellow, oblong-shaped, scored, film-coated tablets marked with “ucb 500” on one side.
• 750 mg KEPPRA tablets are orange, oblong-shaped, scored, film-coated tablets marked with “ucb 750” on one side.
• 1000 mg KEPPRA tablets are white, oblong-shaped, scored, film-coated tablets marked with “ucb 1000” on one side.
• KEPPRA oral solution is a clear, colorless, grape-flavored liquid.

I could not find an injectable formulation of Keppra --98.70.132.83 (talk) 23:06, 2 June 2010 (UTC)

other side effects from those listed

When I take Keppra, I will have a total loss of Ego. I will not respond, or even understand anything asked of me. This may be an unusual symptom, but I was told my my doctor that this is not too uncommon. That is why I feel it must be mentioned here until I (Or another) can find a quotable reference to this. (Sorry for editing the main article improperly, and thank you SpikeToronto for patiently explaining this to me.) —Preceding unsigned comment added by 68.189.219.105 (talk) 08:38, 24 October 2010 (UTC)

I am still new to this, but this link is to the PDF of information from the manufacturer about Keppra. It has references and many of the symptoms listed there are simply missing from the main Wikipedia article. Please fix this if you know how. I will fix it as soon as I learn how I am supposed to do this. http://www.keppraxr.com/includes/pdf/Keppra_IR_Current_30E.pdf —Preceding unsigned comment added by 68.189.219.105 (talk) 20:56, 24 October 2010 (UTC)

I experienced posterior reversible encepalopathy syndrome on 1st December 2018 and was treated with Keppra (levetiracetam, bi daily untill 8th February 2019 Effects noticed were, extreme irritability,aggression, and alternatively depression. As well as short term memory deficit. These characteristics were noted by friends and peer groups. Since this drug was ceased on 8th February, I have noticed a significant improvement in mood,as have friends and others have also observed. I hope in the coming months and weeks the effects of this drug will have completely dissapated from my system. To friends and relatives of patients, whose loved ones are are on a short course of this drug, take heart. The side effects may well disappear after the drug is ceased. If however this is not the case, consult your health professional to see if the medication can be modified or changed. — Preceding unsigned comment added by Lise kvist (talk • contribs) 09:28, 23 February 2019 (UTC)

Choline

There are quite a few Racetams, but Levitiracetam is the ONLY one that is an ANTI-Cholinergic. This means it inhibits cross-hemisphere communication in the brain.

I will be testing Piracetam this next month. Perhaps it will control my seizures without basically making me completely brain-dead. (Most Racetams have anti-convulsive properties.) — Preceding unsigned comment added by 68.189.219.105 (talk) 20:58, 28 October 2010

My own negative opinion

I believe this junk is useless for most people. I believe it is only promoted by the pharmaceutical companies because it is one of the more profitable possible treatments for seizures to make and sell. (I need a citation for this obviously) Levitaracetam winds up costing thousands of USD per kilogram. Conversely, Piracetam is easily less than a hundred USD per kilogram. — Preceding unsigned comment added by 68.189.219.105 (talk) 20:58, 28 October 2010

As far as I can tell, the indications for levetiracetam and piracetam are totally different, perhaps even opposite in terms of effects with calcium, so it is meaningless to compare their prices. --IO Device (talk) 23:10, 6 June 2013 (UTC)

Just another note

Another side affects of levetiracetam is heavy weight loss and mood swing positive side is defintely controlling the seizures and also I had taken medicine while feeding my baby around a year , could not find any developmental problems or delays in my child —Preceding unsigned comment added by padma divakaruni68.126.151.18 (talk) 23:17, 24 March 2011 (UTC)

No mention of widely known emotional side effects

This article looks like a c/p reprint of a pharma brochure, with no mention of how Keppra is viewed in popular culture. Keppra is well known to cause dramatic personality changes in people. A doctor I know calls it "the divorce drug." Could someone more qualified to speak to this topic add a section to the article? Ubruni (talk) 00:52, 5 May 2012 (UTC)

It looks like some stuff about emotional and behavioral adverse effects is in the article now, if not as emphatically as you might prefer.

I just wanted to mention, you don't need to be "more qualified" to add anything to an article, you just need qualified sources. You need to know how to find, read, understand, and cite one or more articles, reports, etc. by a respectable source. Of course, now and then one makes a leap of faith with a source that seems legit, and then it turns out not to be. But that's a better mistake to make than to leave out information, waiting for someone else to do the work for you.

I'm saying, with a few exceptions, we're mostly all amateurs here. Well-practiced amateurs, in some cases, but everyone has to start somewhere. You're just as qualified as anyone to be a Wikipedia editor. I'm saying, "Be bold in updating articles"!

--Ben Culture (talk) 07:58, 10 December 2012 (UTC)

Response from User: Sean Moore, 4/5/13 Not sure how the etiquette works for editing this forum but in an attempt to "be bold" with my amateur status I wanted to offer my own experience with said medication. I have been on Depakote, Topiramate, and now Keppra. The only difference I noticed between Depakote and Topiramate was that one added weight and one caused weight loss. Otherwise they all work fairly well in controlling my JME. Topiramate also had more noticeable short term memory loss as well as tingling early on. My main complaint and the reason I have switched 3 times now is because of my subtle recognition of the sedation caused. I wasn't happy with the memory loss but I wasn't upset either I just took it in stride. I thought it was a personal characteristic until I realized I had the same attitude towards death. Noting and being warned of the effects of depression and suicide, I was vigilant but never felt depressed and felt like the statistical increase in suicide wasn't due to depression but rather a mute feeling. A previous contributor noted the "brain dead" feeling which I feel is often considered the memory loss but from personal interpretation I would tie it to a feeling of detachment. Again this has been my main concern especially when I fully recognized it. Now my doctor recommends a dosage of 2000mg levetiracetam 2x a day, I am currently taking 1000mg twice daily fearing the effects I choose to deal occassional seizures but would love any information on alternative treatments. I want to get away from the 'dirty drugs' but realize it may be necessary evil to live with please offer input/experiences — Preceding unsigned comment added by 184.170.124.73 (talk) 21:17, 5 April 2013 (UTC)

Assay of Levetiracetam

The edit of 09:01, 11 December 2011 by 14.96.168.254 created the subsection "Assay of Levetiracetam" but incorrectly (see MOS:HEAD) included a cite ref in the subsection heading. Do you have access to the cited source? If so, would you move the cite ref to the appropriate place within the body text of that subsection, or at least explain here what part(s) of that subsection the source does and doesn't support? Thanks, --Rich Janis (talk) 04:34, 10 October 2013 (UTC)

Keppra28 Edits

We made changes to strengthen the lead section and provided more information about special populations, mechanism of action, and adverse effects. We also added new sections on warnings and pharmacokinetics. Furthermore, we removed any information that was not properly cited or cited from unreliable sources. — Preceding unsigned comment added by Keppra28 (talk • contribs) 07:45, 5 November 2015 (UTC)

Course Peer Review Edit Suggestions

-Does this draft submission reflect a neutral point of view (yes/no)? Yes -Are the points included verifiable with cited published material (yes/no)? Yes -What recommendations can you provide your colleague for improvement of their draft? Suggestions for improvement include using lay language and correcting medical jargon such as “renal excretion” or “CNS” (there was no explanation or statement that CNS stands for central nervous system) so that the information can be more clear to the general public. In addition, there are sections that are not relevant to the general public such as the information on special populations, absorption, distribution, metabolism, and excretion of levetiracetam. In addition, the “measurement in bodily fluids” section is difficult to understand, probably not relevant to the public, and not clear in the conclusions of therapeutic drug monitoring methods of levetiracetam. — Preceding unsigned comment added by Meghanw27 (talk • contribs) 19:14, 9 November 2015 (UTC)