Talk:Oxford Biomedica

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Hi, I have some factual updates for the Oxford BioMedica Wikipedia page. I have included these (with links to sources) below.

Industry: Biotech Revenue: 18.8 Million GDP£ (May 2016)

Number of employees: 250

Oxford BioMedica (LSE: OXB) is a gene and cell therapy group. It was established in 1995 as a spin- out from Oxford University.

Please find below some new information on the company to be updated on the Wikipedia page.

(Redacted)

Hello, and thank you for your proposed changes. I have updated the financial figures. However, the final paragraph (which I removed) appears to be copied or closely paraphrased from Oxford BioMedica's press releases. Wikipedia is an open-source project: we are licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License, which permits our readers to reuse our text for whatever purpose they desire. As a result, copyrighted text for which we lack permission to reuse is incompatible with our free license, and cannot be included in our articles except under extremely limited circumstances as detailed in the Non-free content policy. If you or your organization holds the copyright to your proposed text and is willing to release it under a free license, it is possible to grant Wikipedia permission for reuse by following the instructions at Wikipedia:Declaration of consent for all enquiries. But the preferred solution is to simply rewrite the text in your own words, which has the added benefit of maintaining a consistent editorial tone across Wikipedia's articles. Altamel (talk) 19:57, 25 December 2016 (UTC)

Updated OXB Information

Partnerships

In 2013, Oxford BioMedica and Novartis signed an agreement for the manufacture of clinical grade material using Oxford BioMedica’s LentiVector® gene delivery technology.

In October 2014, Oxford BioMedica announced a second partnership with Novartis for the non-exclusive development and commercialisation licence in oncology under Oxford BioMedica’s LentiVector® platform. Under this agreement, Oxford BioMedica manufactures lentiviral vectors expressing the gene therapy CTL019/CART-019 [Link]. In December 2016, the Company noted the findings reported by Novartis on CTL-019 at the 58th American Society of Hematology Annual Meeting.

Pipeline

The pipeline includes treatments for cancer, Parkinson's disease and retinopathy. The Company's early stage development pipeline includes preclinical candidates for Stargardt disease, motor neuron disease, spinal muscular atrophy and AIDS.

OXB-102 for Parkinsons Disease is ready to enter Phase I/II clinical trials. OXB202 is in preparation for Phase I/Iia trials for corneal graft rejection. OXB-302 is a pre-clinical CAR-T 5TA targeting cancer. OXB-201 has completed is ready to enter Phase II clinical trials for Wet AMD.

Oxford BioMedica has partnered SAR 422459 and SAR 421869 with Sanofi targeting Stargardt disease and Usher syndrome type 1B respectively.

The Company also has additional IP enables royalty bearing project with Novartis, Immune Design and GlaxoSmithKline.

TroVax, now called OXB-301, a therapeutic vaccine for multiple solid cancers, is in Phase III development in collaboration with Sanofi-Aventis. TroVax failed in a key kidney cancer test in 2008 which caused a dramatic drop in Oxford BioMedica's share price.

Finance

Oxford BioMedica raised £20 million in a firm placing and open offer in 2010. In 2012, the Company raised £16m in a placing and open offer. In 2013, Oxford BioMedica was awarded funding of £7.1m under the UK Government's Advanced Manufacturing Supply Chain Initiative (AMSCI), in recognition of the Company's potential to become a world-leader in Advanced Therapy Medicinal Product (ATMP) manufacture and supply chain expertise. In May 2014, Oxford BioMedica raised £25.7m in a fundraising and open offer. In February 2016, Oxford BioMedica raised £8.1 million in a placing. The Company raised net proceeds of £10 million in a Placing in September 2016. — Preceding unsigned comment added by 151.237.232.130 (talk) 10:07, 4 January 2017 (UTC)

References