Talk:Proximal tubule

It

it absorps other useful materials it releases waste materials

and helps pump blood vessels

Table of reabsorption values wrong. —Preceding unsigned comment added by 129.98.121.227 (talk) 00:22, 15 October 2009 (UTC)

Some refs

protein resorption is an interesting area, megalin and cubilin fairly new,

$ eutilsnew -v -xml -out xxxx '"brush border" albumin endocytic'

Terryn, S; Vandenabeele, F; Smolders, I; Moreels, M; Devuyst, O; Steels, P; Van Kerkhove, E (Aug-2007). "A primary culture of mouse proximal tubular cells, established on collagen-coated membranes". American journal of physiology. Renal physiology. 293 (2): F476-85. doi:10.1152/ajprenal.00363.2006. PMC 10.1152/ajprenal.00363.2006. PMID 17475898. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link)

Odera, K; Takahashi, R (Oct-2007). "Age-related change of endocytic receptors megalin and cubilin in the kidney in rats". Biogerontology. 8 (5): 505–15. doi:10.1007/s10522-007-9093-7. PMC 10.1007/s10522-007-9093-7. PMID 17453355. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link)

Devuyst, O; Auzanneau, C; Courtoy, PJ (2005). "Chloride channels and endocytosis: new insights from Dent's disease and ClC-5 knockout mice". Nephron. Physiology. 99 (3): p69-73. doi:10.1159/000083210. PMC 10.1159/000083210. PMID 15637424. {{cite journal}}: |pages= has extra text (help); Check |pmc= value (help)CS1 maint: date and year (link)

Devuyst, O (2004). "Chloride channels and endocytosis: new insights from Dent's disease and CLC-5 knockout mice". Bulletin et mémoires de l'Académie royale de médecine de Belgique. 159 (Pt 2): 212–7. PMID 15615095.{{cite journal}}: CS1 maint: date and year (link)

Yammani, RR; Dahms, NM; Seetharam, B (1-May-2003). "Transcobalamin II receptor interacts with megalin in the renal apical brush border membrane". The Journal of membrane biology. 193 (1): 57–66. doi:10.1007/s00232-002-2007-3. PMC 10.1007/s00232-002-2007-3. PMID 12879166. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link)

Yammani, RR; Seetharam, S; Moulder, JE; Dahms, NM; Seetharam, B (Aug-2002). "Loss of albumin and megalin binding to renal cubilin in rats results in albuminuria after total body irradiation". American journal of physiology. Regulatory, integrative and comparative physiology. 283 (2): R339-46. doi:10.1152/ajpregu.00752.2001. PMC 10.1152/ajpregu.00752.2001. PMID 12121845. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link)

Gburek, J; Willnow, TE; Fyfe, JC; Nowacki, W; Jacobsen, C; Moestrup, SK; Christensen, EI (Feb-2002). "Megalin and cubilin are endocytic receptors involved in renal clearance of hemoglobin". Journal of the American Society of Nephrology : JASN. 13 (2): 423–30. PMID 11805171. {{cite journal}}: Check date values in: |date= (help)CS1 maint: date and year (link)

Le Panse, S; Nielsen, S; Ronco, P; Verroust, P; Christensen, EI (Mar-1997). "Internalization and recycling of glycoprotein 280 in epithelial cells of yolk sac". European journal of cell biology. 72 (3): 257–67. PMID 9084988. {{cite journal}}: Check date values in: |date= (help)CS1 maint: date and year (link)

Cessac-Guillemet, AL; Borot, C; Bakala, H; Perichon, M; Schaeverbeke, M; Schaeverbeke, J (Jul-1996). "Characterization and distribution of albumin binding protein in normal rat kidney". The American journal of physiology. 271 (1 Pt 2): F101-7. PMID 8760249. {{cite journal}}: Check date values in: |date= (help)CS1 maint: date and year (link)

Jackman, MR; Ellis, JA; Luzio, JP (Sep-1994). "Inhibition of apical but not basolateral endocytosis of ricin and folate in Caco-2 cells by cytochalasin D." Journal of cell science. 107 ( Pt 9): 2547–56. PMID 7844170. {{cite journal}}: Check date values in: |date= (help)CS1 maint: date and year (link)

Bakala, H; Sudey, I; Schaeverbeke, J (1990). "Binding of 125I-labelled albumin by isolated rat renal brush-border membrane vesicles. Evidence for uptake and internalization process". The International journal of biochemistry. 22 (10): 1189–94. PMID 2289625.{{cite journal}}: CS1 maint: date and year (link)

albumin resorption, megalin and cubulin, toxicity and protection

eutilsnew -v -xml -maxcnt 15 -out xxxx '"proximal tubule" kidney albumin endocytic'

Thrailkill, KM; Bunn, RC; Cockrell, GE; Moreau, CS; Mackintosh, S; Edmondson, RD; Fowlkes, JL (Jul-2009). "Microalbuminuria in type 1 diabetes is associated with enhanced excretion of the endocytic multiligand receptors megalin and cubilin". Diabetes care. 32 (7): 1266–8. doi:10.2337/dc09-0112. PMC 10.2337/dc09-0112. PMID 19366958. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link)

Hosaka, K; Iino, N; Hosojima, M; Sato, H; Kaseda, R; Yamamoto, K; Kobayashi, A; Gejyo, F; Saito, A (Jun-2009). "Megalin and nonmuscle myosin heavy chain IIA interact with the adaptor protein Disabled-2 in proximal tubule cells". Kidney international. 75 (12): 1308–15. doi:10.1038/ki.2009.85. PMC 10.1038/ki.2009.85. PMID 19340093. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link)

Hosojima, M; Yamamoto, K; Kaseda, R; Soma, T; Kobayashi, A; Suzuki, A; Kabasawa, H; Takeyama, A; Ikuyama, K; Iino, N; Nishiyama, A; Thekkumkara, TJ; Takeda, T; Suzuki, Y; Gejyo, F; Saito, A (Feb-2009). "Regulation of megalin expression in cultured proximal tubule cells by angiotensin II type 1A receptor- and insulin-mediated signaling cross talk". Endocrinology. 150 (2): 871–8. doi:10.1210/en.2008-0886. PMC 10.1210/en.2008-0886. PMID 18927221. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link)

Motoyoshi, Y; Saito, A; Pastan, I; Willnow, TE; Mizutani, S; Ichikawa, I (Nov-2008). "Megalin contributes to the early injury of proximal tubule cells during nonselective proteinuria". Kidney international. 74 (10): 1262–9. doi:10.1038/ki.2008.405. PMC 10.1038/ki.2008.405. PMID 18769366. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link)

Terryn, S; Vandenabeele, F; Smolders, I; Moreels, M; Devuyst, O; Steels, P; Van Kerkhove, E (Aug-2007). "A primary culture of mouse proximal tubular cells, established on collagen-coated membranes". American journal of physiology. Renal physiology. 293 (2): F476-85. doi:10.1152/ajprenal.00363.2006. PMC 10.1152/ajprenal.00363.2006. PMID 17475898. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link)

Odera, K; Takahashi, R (Oct-2007). "Age-related change of endocytic receptors megalin and cubilin in the kidney in rats". Biogerontology. 8 (5): 505–15. doi:10.1007/s10522-007-9093-7. PMC 10.1007/s10522-007-9093-7. PMID 17453355. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link)

Caruso-Neves, C; Cai, H; Souza-Menezes, J; Guggino, WB (5-Dec-2006). "PKB and megalin determine the survival or death of renal proximal tubule cells". Proceedings of the National Academy of Sciences of the United States of America. 103 (49): 18810–5. doi:10.1073/pnas.0605029103. PMC 10.1073/pnas.0605029103. PMID 17121993. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link)

Lazzara, MJ (Jan-2007). "Model of albumin reabsorption in the proximal tubule". American journal of physiology. Renal physiology. 292 (1): F430-9. doi:10.1152/ajprenal.00010.2006. PMC 10.1152/ajprenal.00010.2006. PMID 16954345. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link)

Birn, H (Jul-2006). "The kidney in vitamin B12 and folate homeostasis: characterization of receptors for tubular uptake of vitamins and carrier proteins". American journal of physiology. Renal physiology. 291 (1): F22-36. doi:10.1152/ajprenal.00385.2005. PMC 10.1152/ajprenal.00385.2005. PMID 16760376. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link)

Thelle, K; Vorum, H; Ørskov, H; Birn, H (Apr-2006). "Characterization of proteinuria and tubular protein uptake in a new model of oral L-lysine administration in rats". Kidney international. 69 (8): 1333–40. doi:10.1038/sj.ki.5000272. PMC 10.1038/sj.ki.5000272. PMID 16508656. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link)

Londono, I (Dec-2005). "Glomerular handling of native albumin in the presence of circulating modified albumins by the normal rat kidney". American journal of physiology. Renal physiology. 289 (6): F1201-9. doi:10.1152/ajprenal.00027.2005. PMC 10.1152/ajprenal.00027.2005. PMID 16014576. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link)

Devuyst, O; Auzanneau, C; Courtoy, PJ (2005). "Chloride channels and endocytosis: new insights from Dent's disease and ClC-5 knockout mice". Nephron. Physiology. 99 (3): p69-73. doi:10.1159/000083210. PMC 10.1159/000083210. PMID 15637424. {{cite journal}}: |pages= has extra text (help); Check |pmc= value (help)CS1 maint: date and year (link)

Devuyst, O (2004). "Chloride channels and endocytosis: new insights from Dent's disease and CLC-5 knockout mice". Bulletin et mémoires de l'Académie royale de médecine de Belgique. 159 (Pt 2): 212–7. PMID 15615095.{{cite journal}}: CS1 maint: date and year (link)

Hryciw, DH; Lee, A; Lensink, IL; Kumar, S; Guggino, WB; Cook, DI; Pollock, CA; Poronnik, P (31-Dec-2004). "Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells". The Journal of biological chemistry. 279 (53): 54996–5007. doi:10.1074/jbc.M411491200. PMC 10.1074/jbc.M411491200. PMID 15489223. {{cite journal}}: Check |pmc= value (help); Check date values in: |date= (help)CS1 maint: date and year (link) CS1 maint: unflagged free DOI (link)

McTaggart, SJ; Harris, PJ; Jones, CL (2004). "Role of isoprenoids in cytoskeleton integrity and albumin endocytosis by opossum kidney cells". Nephron. Experimental nephrology. 97 (3): e77-85. doi:10.1159/000078641. PMC 10.1159/000078641. PMID 15292678. {{cite journal}}: Check |pmc= value (help)CS1 maint: date and year (link)

PCT

Why is glucose and amino acids reabsorbed in the proximal convoluted tuble Adilajojo. (talk) 05:05, 25 August 2022 (UTC)

Hi Adilajojo, Wikipedia talk pages are not forums or discussion boards, so posts here should be limited to discussions on improving the article. It is unlikely anyone will reply to your question, so I suggest reading about it and taking your query elsewhere. |→ Spaully ^~talk~  12:29, 25 August 2022 (UTC)