To Live and Die in L.A. may refer to:
- To Live and Die in L.A. (film), a 1985 crime movie directed by William Friedkin
- To Live and Die in L.A. (soundtrack), the soundtrack to the movie by Wang Chung
- "To Live and Die in L.A." (Wang Chung song), a 1985 single from the soundtrack
- To Live and Die in L.A. (soundtrack), the soundtrack to the movie by Wang Chung
- "To Live & Die in L.A." (song), a 1996 single by Makaveli
- To Live and Die in L.A. (novel), a 1984 novel by former Secret Service agent Gerald Petievich; the basis of the movie
- To Live and Die in L.A. (podcast), an investigative and true crime podcast