Togavirus 5′ plus strand cis-regulatory element
(Redirected from Togavirus 5' plus strand cis-regulatory element)
The Togavirus 5′ plus strand cis-regulatory element is an RNA element which is thought to be essential for both plus and minus strand RNA synthesis.[1]
| Togavirus 5′ plus strand cis-regulatory element | |
|---|---|
 Predicted secondary structure and sequence conservation of Toga_5_CRE | |
| Identifiers | |
| Symbol | Toga_5_CRE |
| Rfam | RF00470 |
| Other data | |
| RNA type | Cis-reg |
| Domain(s) | Viruses |
| SO | SO:0000233 |
| PDB structures | PDBe |
Genus Alphavirus belongs to the family Togaviridae. Alpha viruses contain secondary structural motifs in the 5′ UTR that allow them to avoid detection by IFIT1.[2]
See also
editReferences
edit- ^ Frolov I, Hardy R, Rice CM (November 2001). "Cis-acting RNA elements at the 5′ end of Sindbis virus genome RNA regulate minus- and plus-strand RNA synthesis". RNA. 7 (11): 1638–1651. doi:10.1017/S135583820101010X. PMC 1370205. PMID 11720292.
- ^ Hyde JL, Gardner CL, Kimura T, White JP, Liu G, Trobaugh DW, Huang C, Tonelli M, Paessler S, Takeda K, Klimstra WB, Amarasinghe GK, Diamond MS (February 2014). "A viral RNA structural element alters host recognition of nonself RNA". Science. 343 (6172): 783–787. doi:10.1126/science.1248465. PMC 4209899. PMID 24482115.
External links
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