UDP-N-acetylglucosamine—decaprenyl-phosphate N-acetylglucosaminephosphotransferase
UDP-N-acetylglucosamine---decaprenyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.35, GlcNAc-1-phosphate transferase, UDP-GlcNAc:undecaprenyl phosphate GlcNAc-1-phosphate transferase, WecA, WecA transferase) is an enzyme with systematic name UDP-N-acetyl-alpha-D-glucosamine:trans,octacis-decaprenyl-phosphate N-acetylglucosaminephosphotransferase.[1] This enzyme catalyses the following chemical reaction
| UDP-N-acetylglucosamine---decaprenyl-phosphate N-acetylglucosaminephosphotransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.8.35 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- UDP-N-acetyl-alpha-D-glucosamine + trans,octacis-decaprenyl phosphate UMP + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
This enzyme is isolated from Mycobacterium tuberculosis and Mycobacterium smegmatis.
References
edit- ^ Jin Y, Xin Y, Zhang W, Ma Y (September 2010). "Mycobacterium tuberculosis Rv1302 and Mycobacterium smegmatis MSMEG_4947 have WecA function and MSMEG_4947 is required for the growth of M. smegmatis". FEMS Microbiology Letters. 310 (1): 54–61. doi:10.1111/j.1574-6968.2010.02045.x. PMID 20637039.
External links
edit- UDP-N-acetylglucosamine---decaprenyl-phosphate+N-acetylglucosaminephosphotransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
