The UnaL2 LINE 3′ element is an RNA element found in the UnaL2 LINE (long interspersed nuclear element) and partner SINE (short interspersed nuclear element) from eel.[1] This conserved element is a stem-loop that is critical for their retrotransposition found in their 3′ end. The first step of retrotransposition is the recognition of their 3′ tails by UnaL2-encoded reverse transcriptase. The NMR structure of a 17-nucleotide RNA derived from the 3′ tail of UnaL2 has been determined.[1]
UnaL2 LINE 3′ element | |
---|---|
Identifiers | |
Symbol | UnaL2 |
Rfam | RF00436 |
Other data | |
RNA type | Cis-reg |
Domain(s) | Eukaryota |
SO | SO:0000233 |
PDB structures | PDBe |
References
edit- ^ a b Baba S, Kajikawa M, Okada N, Kawai G (September 2004). "Solution structure of an RNA stem-loop derived from the 3′ conserved region of eel LINE UnaL2". RNA. 10 (9): 1380–1387. doi:10.1261/rna.7460104. PMC 1370625. PMID 15273327.