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Michel Kahaleh

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Michel Kahaleh is an American gastroenterologist and an expert in therapeutic endoscopy.

Kahaleh overseeing an Endoscopy during a live course workshop in 2017

He is a Professor of Medicine, and is currently the Clinical Director of Gastroenterology, Chief of Endoscopy, and Director of the Pancreas Program at the Department of Medicine, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey.[1] He is the Founder and Director of the Therapeutic Endoscopic Ultrasound Society.[2] He is the Founder and CEO of the non-profit organization Innovative Digestive Health Education & Research Inc. (IDHER) since 2018[3] He is also the Founder and CEO of the non-profit organization Foundation for Interventional and Therapeutic Endoscopy (FITE) since 2020[4]

Medical and research career

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Trained in Erasme Hospital, University of Brussels by Michel Cremer and Jacques Deviere, he became the leader of the Pancreatico-Biliary group at the University of Virginia before joining Weill Cornell Medical College as the Chief of Endoscopy and Pancreas Program Director in July 2011.  In January 2018, Kahaleh joined Rutgers Robert Wood Johnson University as clinical director of gastroenterology and chief of endoscopy. Kahaleh's research is focused on interventional endoscopy, and the use of new devices to diagnose and treat various gastrointestinal disorders.

Kahaleh has conducted 30 clinical research studies[5] since 15 years and published 320 papers[6] and 200 national and international scientific presentations.[7]

 
Kahaleh doing Per-oral endoscopic myotomy with Dr. Haruhiro inoue

Kahaleh has been involved in in-vivo projects aiming at improving minimally invasive procedures such as per-oral endoscopic myotomy (POEM)[8][9] for achalasia,[10] gallbladder drainage,[11] biliary[12] and pancreatic[13][14] decompression. He is credited with creating a new endoscopic approach for biliary obstructions in altered anatomy patients called EUS-directed transgastric endoscopic retrograde cholangiopancreatography (EDGE).[15][16][17]

He helped develop and validate new diagnostic criteria for improving accuracy in diagnosis of bile duct cancer using confocal laser endomicroscopy[18][19][20][21] called the Paris classification.[22][23] He led a team of expert endoscopists to develop and validate the Monaco classification[24] diagnostic criteria for bile duct cancer using the SpyGlass® Direct Visualization System for cholangioscopy.

Kahaleh was one of the first to publish on radio frequency ablation (RFA) for bile duct cancer and pancreatic cancer therapy using Nagy Habib's probe in the United States. He was the first to publish a clinical trial on photodynamic therapy (PDT) in the United States for bile duct cancer.[25][26] He was the first to conduct a pre-clinical study of a radio frequency ablation probe using endoscopic ultrasound (EUS-RFA) meant for treating pancreatic cancer.[27] The EUS-RFA probe was created by Nagy Habib and has been successfully used in humans after the pre-clinical study.[28]

Kahaleh has further published papers on additional minimally invasive endoscopic treatment for several conditions including pancreatic fluid collections,[29] gastroparesis,[30] gastric outlet obstruction,[31] obesity weight loss procedures,[32] esophageal tumors[33][34] and others.

Kahaleh has created a personalized training program which allowed him to train physicians on endoscopic submucosal dissection (ESD) and POEM in the US, Italy, Spain, Colombia, Nicaragua, Ecuador, Mexico and Argentina.[35]

Non-profit Career

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Dr. Kahaleh is the Founder and Director of the Therapeutic Endoscopic Ultrasound Society.[2] He is the Founder and CEO of the non-profit organization Innovative Digestive Health Education & Research Inc. (IDHER) since 2018[3] He is also the Founder and CEO of the non-profit organization Foundation for Interventional and Therapeutic Endoscopy (FITE) since 2020[4]

As the Founder of the Therapeutic Endoscopic Ultrasound Society,[36] along with colleague co-founder Todd Baron, Kahaleh and Monica Gaidhane have hosted the annual consortium on Therapeutic EUS during the Digestive Disease Week for the past 9 years.[37]

As the Founder of the Innovative Digestive Health Education & Research Inc. (IDHER),[3] along with co-founder Monica Gaidhane, Kahaleh has directed many continuing medical education conferences for Advanced Endoscopy including the annual Mid-Atlantic Gastrointestinal Interventional Course (MAGIC),[38] annual Mid-Atlantic Bariatric Endoscopy Course (MALBEC) [39] and annual Emerging Pancreatic Innovations Course (EPIC)[40] for the past 4 years.

Dr. Kahaleh helped develop the Foundation for Interventional and Therapeutic Endoscopy (FITE)[4] to fulfill unmet needs of Interventional and Therapeutic Endoscopists.

All three of his non-profit organizations focus on education, practice, research and improving patient outcomes with minimally invasive treatments.[2][3][4]

Honors and awards

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References

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  1. ^ "Rutgers Gastroenterology".
  2. ^ a b c "TEUSSOCIETY".
  3. ^ a b c d Gaidhane, Monica (2018). "Innovative Digestive Health Education and Research". IDHER.
  4. ^ a b c d Gaidhane, Monica (c. 2022). "Foundation for Interventional and Therapeutic Endoscopy (FITE)".
  5. ^ "Clinical Trials Gov Listing of active studies".
  6. ^ "Listing of Publications".
  7. ^ "Michel Kahaleh biography".
  8. ^ Kumta, Nikhil A.; Mehta, Shivani; Kedia, Prashant; Weaver, Kristen; Sharaiha, Reem Z.; Fukami, Norio; Minami, Hitomi; Casas, Fernando; Gaidhane, Monica (September 2014). "Peroral endoscopic myotomy: establishing a new program". Clinical Endoscopy. 47 (5): 389–397. doi:10.5946/ce.2014.47.5.389. ISSN 2234-2400. PMC 4198553. PMID 25324996.
  9. ^ Tyberg, Amy; Sharaiha, Reem Z.; Familiari, Pietro; Costamagna, Guido; Casas, Fernando; Kumta, Nikhil A.; Barret, Maximilien; Desai, Amit P.; Schnoll-Sussman, Felice (January 2018). "Peroral endoscopic myotomy as salvation technique post-Heller: International experience". Digestive Endoscopy. 30 (1): 52–56. doi:10.1111/den.12918. ISSN 1443-1661. PMID 28691186. S2CID 24703905.
  10. ^ "Poem for Achalasia video". 6 June 2015.
  11. ^ Tyberg, Amy; Saumoy, Monica; Sequeiros, Enrique V.; Giovannini, Marc; Artifon, Everson; Teoh, Anthony; Nieto, Jose; Desai, Amit P.; Kumta, Nikhil A. (January 2018). "EUS-guided Versus Percutaneous Gallbladder Drainage: Isn't It Time to Convert?". Journal of Clinical Gastroenterology. 52 (1): 79–84. doi:10.1097/MCG.0000000000000786. ISSN 1539-2031. PMID 28009687. S2CID 12422882.
  12. ^ Sharaiha, Reem Z.; Khan, Muhammad Ali; Kamal, Faisal; Tyberg, Amy; Tombazzi, Claudio R.; Ali, Bilal; Tombazzi, Claudio; Kahaleh, Michel (May 2017). "Efficacy and safety of EUS-guided biliary drainage in comparison with percutaneous biliary drainage when ERCP fails: a systematic review and meta-analysis". Gastrointestinal Endoscopy. 85 (5): 904–914. doi:10.1016/j.gie.2016.12.023. ISSN 1097-6779. PMID 28063840.
  13. ^ Doshi, Rushabh; Rizk, Nada; Tyberg, Amy; Sharaiha, Reem Z.; Kahaleh, Michel (July 2016). "EUS-guided pancreatic drainage for recurrent pancreatitis". Gastrointestinal Endoscopy. 84 (1): 186–187. doi:10.1016/j.gie.2016.01.033. ISSN 1097-6779. PMID 26802203.
  14. ^ Tyberg, Amy; Sharaiha, Reem Z.; Kedia, Prashant; Kumta, Nikhil; Gaidhane, Monica; Artifon, Everson; Giovannini, Marc; Kahaleh, Michel (January 2017). "EUS-guided pancreatic drainage for pancreatic strictures after failed ERCP: a multicenter international collaborative study". Gastrointestinal Endoscopy. 85 (1): 164–169. doi:10.1016/j.gie.2016.07.030. ISSN 1097-6779. PMID 27460387.
  15. ^ "Bariatric News".
  16. ^ Kedia, Prashant; Kumta, Nikhil A.; Widmer, Jessica; Sundararajan, Subha; Cerefice, Mark; Gaidhane, Monica; Sharaiha, Reem; Kahaleh, Michel (February 2015). "Endoscopic ultrasound-directed transgastric ERCP (EDGE) for Roux-en-Y anatomy: a novel technique". Endoscopy. 47 (2): 159–163. doi:10.1055/s-0034-1390771. ISSN 1438-8812. PMID 25575353. S2CID 25361525.
  17. ^ Kedia, Prashant; Tarnasky, Paul R.; Nieto, Jose; Steele, Stephen L.; Siddiqui, Ali; Xu, Ming-Ming; Tyberg, Amy; Gaidhane, Monica; Kahaleh, Michel (2018-04-17). "EUS-directed Transgastric ERCP (EDGE) Versus Laparoscopy-assisted ERCP (LA-ERCP) for Roux-en-Y Gastric Bypass (RYGB) Anatomy: A Multicenter Early Comparative Experience of Clinical Outcomes". Journal of Clinical Gastroenterology. 53 (4): 304–308. doi:10.1097/MCG.0000000000001037. ISSN 1539-2031. PMID 29668560. S2CID 4952832.
  18. ^ "pCLE".
  19. ^ "PCLE tiny microscope".
  20. ^ "confocal".
  21. ^ "confocal diagnosis".
  22. ^ Caillol, Fabrice; Filoche, Bernard; Gaidhane, Monica; Kahaleh, Michel (June 2013). "Refined probe-based confocal laser endomicroscopy classification for biliary strictures: the Paris Classification". Digestive Diseases and Sciences. 58 (6): 1784–1789. doi:10.1007/s10620-012-2533-5. ISSN 1573-2568. PMID 23314855. S2CID 7640515.
  23. ^ Kahaleh, Michel; Giovannini, Marc; Jamidar, Priya; Gan, S. Ian; Cesaro, Paola; Caillol, Fabrice; Filoche, Bernard; Karia, Kunal; Smith, Ioana (2015). "Probe-based confocal laser endomicroscopy for indeterminate biliary strictures: refinement of the image interpretation classification". Gastroenterology Research and Practice. 2015: 675210. doi:10.1155/2015/675210. ISSN 1687-6121. PMC 4377502. PMID 25866506.
  24. ^ 1040 Defining imaging criteria for indeterminate biliary strictures utilizing video cholangioscopy: The Monaco Classification. Sethi, Amrita; Shah, Raj J; Itoi, Takao; Moon, Jong Ho; Sejpal, Divyesh V   ; Pleskow, Douglas K.   ; Slivka, Adam   ; Adler, Douglas G.  ; Edmundowicz, Steven A.   ; Kim, Dong Choon   ; Petersen, Bret T; Gress, Frank G.  ; Gaidhane, Monica  ; Kahaleh, Michel. Volume 81, No. 5S : 2015 GASTROINTESTINAL ENDOSCOPY AB188. Digestive Diseases Week 2015
  25. ^ Baisden, Joseph M.; Kahaleh, Michel; Weiss, Geoffrey R.; Sanfey, Hilary; Moskaluk, Christopher A.; Yeaton, Paul; de Lange, Eduard E.; Rich, Tyvin A. (September 2008). "Multimodality Treatment With Helical Tomotherapy Intensity Modulated Radiotherapy, Capecitabine, and Photodynamic Therapy is Feasible and Well Tolerated in Patients With Hilar Cholangiocarcinoma". Gastrointestinal Cancer Research. 2 (5): 219–224. ISSN 1934-7820. PMC 2632558. PMID 19259306.
  26. ^ Kahaleh, Michel; Mishra, Rajnish; Shami, Vanessa M.; Northup, Patrick G.; Berg, Carl L.; Bashlor, Penny; Jones, Petra; Ellen, Kristi; Weiss, Geoffrey R. (March 2008). "Unresectable cholangiocarcinoma: comparison of survival in biliary stenting alone versus stenting with photodynamic therapy". Clinical Gastroenterology and Hepatology. 6 (3): 290–297. doi:10.1016/j.cgh.2007.12.004. ISSN 1542-7714. PMID 18255347.
  27. ^ Gaidhane, Monica; Smith, Ioana; Ellen, Kristi; Gatesman, Jeremy; Habib, Nagy; Foley, Patricia; Moskaluk, Christopher; Kahaleh, Michel (2012). "Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of the Pancreas in a Porcine Model". Gastroenterology Research and Practice. 2012: 431451. doi:10.1155/2012/431451. ISSN 1687-630X. PMC 3459266. PMID 23049547.
  28. ^ Song, Tae Jun; Seo, Dong Wan; Lakhtakia, Sundeep; Reddy, Nageshwar; Oh, Dong Wook; Park, Do Hyun; Lee, Sang Soo; Lee, Sung Koo; Kim, Myung-Hwan (February 2016). "Initial experience of EUS-guided radiofrequency ablation of unresectable pancreatic cancer". Gastrointestinal Endoscopy. 83 (2): 440–443. doi:10.1016/j.gie.2015.08.048. ISSN 1097-6779. PMID 26344883.
  29. ^ Shah, Raj J.; Shah, Janak N.; Waxman, Irving; Kowalski, Thomas E.; Sanchez-Yague, Andres; Nieto, Jose; Brauer, Brian C.; Gaidhane, Monica; Kahaleh, Michel (April 2015). "Safety and efficacy of endoscopic ultrasound-guided drainage of pancreatic fluid collections with lumen-apposing covered self-expanding metal stents". Clinical Gastroenterology and Hepatology. 13 (4): 747–752. doi:10.1016/j.cgh.2014.09.047. ISSN 1542-7714. PMID 25290534.
  30. ^ Kahaleh, Michel; Gonzalez, Jean-Michel; Xu, Ming-Ming; Andalib, Iman; Gaidhane, Monica; Tyberg, Amy; Saumoy, Monica; Baptista Marchena, Alberto Jose; Barthet, Marc (2018-04-12). "Gastric peroral endoscopic myotomy for the treatment of refractory gastroparesis: a multicenter international experience". Endoscopy. 50 (11): 1053–1058. doi:10.1055/a-0596-7199. ISSN 1438-8812. PMID 29649841. S2CID 4793867.
  31. ^ Perez-Miranda, Manuel; Tyberg, Amy; Poletto, Daniel; Toscano, Ernesto; Gaidhane, Monica; Desai, Amit P.; Kumta, Nikhil A.; Fayad, Lea; Nieto, Jose (November–December 2017). "EUS-guided Gastrojejunostomy Versus Laparoscopic Gastrojejunostomy: An International Collaborative Study". Journal of Clinical Gastroenterology. 51 (10): 896–899. doi:10.1097/MCG.0000000000000887. ISSN 1539-2031. PMID 28697151. S2CID 29931015.
  32. ^ Lopez-Nava, Gontrand; Sharaiha, Reem Z.; Vargas, Eric J.; Bazerbachi, Fateh; Manoel, Galvao Neto; Bautista-Castaño, Inmaculada; Acosta, Andres; Topazian, Mark D.; Mundi, Manpreet S. (October 2017). "Endoscopic Sleeve Gastroplasty for Obesity: a Multicenter Study of 248 Patients with 24 Months Follow-Up". Obesity Surgery. 27 (10): 2649–2655. doi:10.1007/s11695-017-2693-7. ISSN 1708-0428. PMID 28451929. S2CID 4924140.
  33. ^ Kumta, Nikhil A.; Saumoy, Monica; Tyberg, Amy; Kahaleh, Michel (February 2017). "Submucosal Tunneling Endoscopic Resection for En Bloc Removal of Large Esophageal Gastrointestinal Stromal Tumors". Gastroenterology. 152 (3): 482–483. doi:10.1053/j.gastro.2016.11.044. ISSN 1528-0012. PMID 27923727.
  34. ^ Kumta, Nikhil A.; Xu, Ming-Ming; Marfatia, Pawan; Pittman, Meredith; Bednarek, Karl; Kahaleh, Michel (2016). "Submucosal tunneling endoscopic resection of a symptomatic leiomyoma in the proximal esophagus". Endoscopy. 48 (S 01): E398. doi:10.1055/s-0042-120705. ISSN 1438-8812. PMID 27997960.
  35. ^ [michelkahaleh.com "Michel Kahaleh Website"]. {{cite web}}: Check |url= value (help)
  36. ^ "Founder".
  37. ^ Gaidhane, Monica. "TEUS Consortium".
  38. ^ Gaidhane, Monica (2020-01-01). "MAGIC Endoscopy". Magic Endoscopy.
  39. ^ Gaidhane, Monica (c. 2019). "MALBEC Endoscopy".
  40. ^ Gaidhane, Monica (2021-01-01). "EPIC Pancreas Live Course".
  41. ^ "Plenary session award".
  42. ^ "Fellow NYSGE 2018".
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