William Curtis House may refer to:
- in the United States
(by state)
- William E. Curtis House, Tampa, Florida, listed on the NRHP in Florida
- William Curtis House (Newton, Massachusetts), listed on the NRHP in Massachusetts
- William A. Curtis House, Raleigh, North Carolina, listed on the NRHP in Wake County, North Carolina
- William D. Curtis House, Sandusky, Ohio, listed on the NRHP in Sandusky, Ohio