William Murrell may refer to:
- William Murrell (physician) (1853–1912), English physician, clinical pharmacologist, and toxicologist
- William Murrell (politician, died 1892), state legislator in Louisiana
- William Murrell Jr. (1845–1932), state legislator in Louisiana
See also
edit- Willie Murrell (1941–2018), American basketball player
- William Murrill (1869–1957), American mycologist