William Pattison may refer to:
- William Pattison (poet) (1706–1727), English poet
- William Pattison (politician) (1830–1896), Australian politician
- William J. Pattison (1921–1943), US Navy sailor, recipient of the Navy Cross, and namesake of the USS William J. Pattison (APD-104)
- William D. Pattison, American geographer; proposer of the four traditions of geography