William Webber may refer to:
- William Webber (criminal) (1877–1936), underworld figure in New York
- William Lloyd Webber (1914–1982), English organist and composer
- William Webber (bishop) (1837–1903), Anglican bishop of Brisbane
- William Webber (surgeon) (1800–1875), English surgeon
- Bill Webber (trade unionist) (1901–1982), Welsh trade union leader
- Bill "Wee Willie" Webber (1929–2010), Philadelphia TV and radio personality