Yuri (Yuriy, Yurii) Smirnov may refer to:
- Yuri Andreyevich Smirnov (1923–1984), Russian linguist
- Yuri Mikhailovich Smirnov (1921–2007), Soviet and Russian mathematician
- Yuriy Smirnov (minister) (born 1948), Ukrainian Minister of Internal Affairs in 2001–2003