Yūsuke Kobayashi may refer to:
- Yūsuke Kobayashi (voice actor) (born 1985), Japanese voice actor
- Yusuke Kobayashi (footballer, born 1983) (小林 優希), Japanese footballer
- Yusuke Kobayashi (footballer, born 1994) (小林 祐介), Japanese footballer
- Yūsuke Kobayashi (judoka) (born 1993), Japanese judoka