In molecular biology, ZNFX1 antisense RNA 1, also known as ZNFX1-AS1 or ZFAS1, is a long non-coding RNA. It is expressed in the lung and mammary gland in mice. Its expression is down-regulated in mammary tumours, it may function as a tumour suppressor gene.[1] The ZNFX1-AS1 gene hosts three snoRNA genes (SNORD12, SNORD12B and SNORD12C)).[1]
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edit- ^ a b Askarian-Amiri ME, Crawford J, French JD, Smart CE, Smith MA, Clark MB, Ru K, Mercer TR, Thompson ER, Lakhani SR, Vargas AC, Campbell IG, Brown MA, Dinger ME, Mattick JS (May 2011). "SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer". RNA. 17 (5): 878–891. doi:10.1261/rna.2528811. PMC 3078737. PMID 21460236.
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