Aescwine or Escwine or Æscwine is an Anglo-Saxon name, whose modern descendant is Ashwin. It translates literally as "ash-tree friend", but can mean a number of things, including "strong/manly friend", or "friendly man."
Notable persons with the name include:
- Æscwine of Essex (494-587), born in ancient Saxony in northern Germany and in 527 he became king of Essex
- Æscwine of Wessex (died circa 676), king of Wessex