(+)-β-Caryophyllene synthase (EC 4.2.3.89, GcoA) is an enzyme with systematic name (2Z,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-β-caryophyllene-forming).[1] This enzyme catalyses the following chemical reaction:
| (+)-β-caryophyllene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.89 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (2E,6E)-farnesyl diphosphate (+)-β-caryophyllene + diphosphate
This enzyme also converts the (+)-β-caryophyllene to (+)-caryolan-1-ol.
References
edit- ^ Nakano C, Horinouchi S, Ohnishi Y (August 2011). "Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus". The Journal of Biological Chemistry. 286 (32): 27980–7. doi:10.1074/jbc.m111.265652. PMC 3151043. PMID 21693706.
External links
edit- (+)-beta-caryophyllene+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
