(2R)-3-sulfolactate dehydrogenase (NADP+)

(2R)-3-sulfolactate dehydrogenase (NADP+) (EC 1.1.1.338, (R)-sulfolactate:NADP+ oxidoreductase, L-sulfolactate dehydrogenase, (R)-sulfolactate dehydrogenase, ComC) is an enzyme with systematic name (2R)-3-sulfolactate:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

(2R)-3-sulfolactate dehydrogenase (NADP+)
Identifiers
EC no.1.1.1.338
CAS no.81210-65-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins
(2R)-3-sulfolactate + NADP+ 3-sulfopyruvate + NADPH + H+

The enzyme from the bacterium Chromohalobacter salexigens can only utilize NADP+.

References

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  1. ^ Denger K, Cook AM (March 2010). "Racemase activity effected by two dehydrogenases in sulfolactate degradation by Chromohalobacter salexigens: purification of (S)-sulfolactate dehydrogenase" (PDF). Microbiology. 156 (Pt 3): 967–74. doi:10.1099/mic.0.034736-0. PMID 20007648.
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