(2Z,6Z)-farnesyl diphosphate synthase (EC 2.5.1.92, cis,cis-farnesyl diphosphate synthase, Z,Z-FPP synthase, zFPS, Z,Z-farnesyl pyrophosphate synthase) is an enzyme with systematic name dimethylallyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 2 isopentenyl units).[1] This enzyme catalyses the following chemical reaction
| (2Z,6Z)-farnesyl diphosphate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.5.1.92 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- dimethylallyl diphosphate + 2 isopentenyl diphosphate 2 diphosphate + (2Z,6Z)-farnesyl diphosphate
This enzyme was originally characterized from the wild hairy tomato Solanum habrochaites.
References
edit- ^ Sallaud C, Rontein D, Onillon S, Jabès F, Duffé P, Giacalone C, Thoraval S, Escoffier C, Herbette G, Leonhardt N, Causse M, Tissier A (January 2009). "A novel pathway for sesquiterpene biosynthesis from Z,Z-farnesyl pyrophosphate in the wild tomato Solanum habrochaites". The Plant Cell. 21 (1): 301–17. doi:10.1105/tpc.107.057885. PMC 2648096. PMID 19155349.
External links
edit- (2Z,6Z)-farnesyl+diphosphate+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
