β-Phellandrene synthase (EC 4.2.3.52, geranyl-diphosphate-cyclizing) (phellandrene synthase, (−)-β-phellandrene synthase, (−)-(4S)-β-phellandrene synthase) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase (cyclizing; β-phellandrene-forming).[1][2][3][4] This enzyme catalyses the following chemical reaction
| β-phellandrene synthase (geranyl-diphosphate-cyclizing) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.52 | ||||||||
| CAS no. | 137010-34-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme requires ion Mn2+.
References
edit- ^ Savage TJ, Hatch MW, Croteau R (February 1994). "Monoterpene synthases of Pinus contorta and related conifers. A new class of terpenoid cyclase". The Journal of Biological Chemistry. 269 (6): 4012–20. PMID 8307957.
- ^ Bohlmann J, Phillips M, Ramachandiran V, Katoh S, Croteau R (August 1999). "cDNA cloning, characterization, and functional expression of four new monoterpene synthase members of the Tpsd gene family from grand fir (Abies grandis)". Archives of Biochemistry and Biophysics. 368 (2): 232–43. doi:10.1006/abbi.1999.1332. PMID 10441373.
- ^ Wagschal K, Savage TJ, Croteau R (1991). "Isotopically sensitive branching as a tool for evaluating multiple product formation by monoterpene cyclases". Tetrahedron. 31: 5933–5944. doi:10.1016/s0040-4020(01)86486-3.
- ^ LaFever RE, Croteau R (March 1993). "Hydride shifts in the biosynthesis of the p-menthane monoterpenes alpha-terpinene, gamma-terpinene, and beta-phellandrene". Archives of Biochemistry and Biophysics. 301 (2): 361–6. doi:10.1006/abbi.1993.1156. PMID 8460944.
External links
edit- (4S)-beta-phellandrene+synthase+(geranyl-diphosphate-cyclizing) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
