1,2-diacylglycerol 3-glucosyltransferase

In enzymology, a 1,2-diacylglycerol 3-glucosyltransferase (EC 2.4.1.157) is an enzyme that catalyzes the chemical reaction

1,2-diacylglycerol 3-glucosyltransferase
Identifiers
EC no.2.4.1.157
CAS no.83744-96-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
UDP-glucose + 1,2-diacylglycerol UDP + 3-D-glucosyl-1,2-diacylglycerol

Thus, the two substrates of this enzyme are UDP-glucose and 1,2-diacylglycerol, whereas its two products are UDP and 3-D-glucosyl-1,2-diacylglycerol.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:1,2-diacylglycerol 3-D-glucosyltransferase. Other names in common use include UDP-glucose:diacylglycerol glucosyltransferase, UDP-glucose:1,2-diacylglycerol glucosyltransferase, uridine diphosphoglucose-diacylglycerol glucosyltransferase, and UDP-glucose-diacylglycerol glucosyltransferase. This enzyme participates in glycerolipid metabolism.

References

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  • Sato N, Murata N (1982). "Lipid biosynthesis in the blue-green-alga (cyanobacterium), Anabaena variabilis. 3. UDP-glucose-diacylglycerol glucosyltransferase activity in vitro". Plant Cell Physiol. 23: 1115–1120.