1-hydroxy-2-naphthoate hydroxylase (EC 1.14.13.135, 1-hydroxy-2-naphthoic acid hydroxylase) is an enzyme with systematic name 1-hydroxy-2-naphthoate,NAD(P)H:oxygen oxidoreductase (2-hydroxylating, decarboxylating).[1][2] This enzyme catalyses the following chemical reaction
| 1-hydroxy-2-naphthoate hydroxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.135 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- 1-hydroxy-2-naphthoate + NAD(P)H + H+ + O2 1,2-dihydroxynaphthalene + NAD(P)+ + H2O + CO2
1-hydroxy-2-naphthoate hydroxylase is involved in chrysene degradation in some bacteria.
References
edit- ^ Deveryshetty J, Phale PS (October 2010). "Biodegradation of phenanthrene by Alcaligenes sp. strain PPH: partial purification and characterization of 1-hydroxy-2-naphthoic acid hydroxylase". FEMS Microbiology Letters. 311 (1): 93–101. doi:10.1111/j.1574-6968.2010.02079.x. PMID 20727010.
- ^ Nayak AS, Sanjeev Kumar S, Santosh Kumar M, Anjaneya O, Karegoudar TB (July 2011). "A catabolic pathway for the degradation of chrysene by Pseudoxanthomonas sp. PNK-04". FEMS Microbiology Letters. 320 (2): 128–34. doi:10.1111/j.1574-6968.2011.02301.x. PMID 21545490.
External links
edit- 1-hydroxy-2-naphthoate+hydroxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
