101st Brigade may refer to:
- 101st Brigade (United Kingdom), 1915 to 1919
- 101st Logistic Brigade of the British Army, formed in 1999
- 101st Brigade for the Protection of the General Staff of the Ukrainian Army
- 101st Territorial Defense Brigade (Ukraine), a unit of the Ukrainian Territorial Defense Forces
- 101st Sustainment Brigade, of the United States Army
- 101st Panzer Brigade of the Wehrmacht