15α-Hydroxydehydroepiandrosterone, abbreviated as 15α-hydroxy-DHEA or 15α-OH-DHEA, is an endogenous metabolite of dehydroepiandrosterone (DHEA).[1][2][3] Both 15α-OH-DHEA and its 3β-sulfate ester, 15α-OH-DHEA-S, are intermediates in the biosynthesis of estetrol from dehydroepiandrosterone (DHEA).[1][2][3]
| |
| Names | |
|---|---|
| IUPAC name
3β,15α-Dihydroxyandrost-5-en-17-one
| |
| Systematic IUPAC name
(3S,3aS,3bR,7S,9aR,9bS,11aS)-3,7-Dihydroxy-9a,11a-dimethyl-2,3,3a,3b,4,6,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthren-1-one | |
| Other names
15α-Hydroxydehydroepiandrosterone; 15α-Hydroxy-DHEA; 15α-OH-DHEA
| |
| Identifiers | |
3D model (JSmol)
|
|
| ChemSpider | |
PubChem CID
|
|
| UNII | |
CompTox Dashboard (EPA)
|
|
| |
| |
| Properties | |
| C19H28O3 | |
| Molar mass | 304.430 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
| |
See also
editReferences
edit- ^ a b Roger Smith (Prof.) (1 January 2001). The Endocrinology of Parturition: Basic Science and Clinical Application. Karger Medical and Scientific Publishers. pp. 91–. ISBN 978-3-8055-7195-1.
- ^ a b J.B. Josimovich (11 November 2013). Gynecologic Endocrinology. Springer Science & Business Media. pp. 32–. ISBN 978-1-4613-2157-6.
- ^ a b Jerome F. Strauss, III; Robert L. Barbieri (13 September 2013). Yen and Jaffe's Reproductive Endocrinology. Elsevier Health Sciences. pp. 257–. ISBN 978-1-4557-2758-2.
 | This article about a steroid is a stub. You can help Wikipedia by expanding it. |