1T-LSD

1T-LSD
Clinical data
Routes of; administration	By mouth, under the tongue
Identifiers
	IUPAC name (6aR,9R)-N,N-diethyl-7-methyl-4-(thiophen-2-yl)methanoyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide;
PubChem CID	170763788;
ChemSpider	129341136;
Chemical and physical data
Formula	C25H27N3O2S
Molar mass	433.57 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(n1cc2C[C@@H]3C(=C[C@H](CN3C)C(=O)N(CC)CC)c3cccc1c32)c1cccs1;

1T-LSD (N1-(thiophene-2-carbonyl)-lysergic acid diethylamide, SYN-L-021) is an acylated derivative of lysergic acid diethylamide (LSD), which has been sold as a designer drug. It was first identified in Japan in 2023 on blotter paper misrepresented as containing 1D-LSD, but which on analysis was determined to contain 1T-LSD instead.^[1] It was also detected in Germany around the same time.^[2]

References

^ Okada Y, Ueno K, Nishiwaki N, Nishimura T, Segawa H, Yamamuro T, et al. (July 2023). "Identification of 1-(thiophene-2-carbonyl)-LSD from blotter paper falsely labeled "1D-LSD"". Forensic Toxicology. 42 (1): 93–101. doi:10.1007/s11419-023-00668-8. PMID 37421500. S2CID 259374662.
^ "New psychoactive substances - the current situation in Europe" (PDF). European Drug Report. European Union Drugs Agency (EUDA). 2024.

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[1] Okada Y, Ueno K, Nishiwaki N, Nishimura T, Segawa H, Yamamuro T, et al. (July 2023). "Identification of 1-(thiophene-2-carbonyl)-LSD from blotter paper falsely labeled "1D-LSD"". Forensic Toxicology. 42 (1): 93–101. doi:10.1007/s11419-023-00668-8. PMID 37421500. S2CID 259374662.

[2] "New psychoactive substances - the current situation in Europe" (PDF). European Drug Report. European Union Drugs Agency (EUDA). 2024.

[1]

[2]

Clinical data

Routes of administration	By mouth, under the tongue
Identifiers
IUPAC name (6aR,9R)-N,N-diethyl-7-methyl-4-(thiophen-2-yl)methanoyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
PubChem CID	170763788
ChemSpider	129341136
Chemical and physical data
Formula	C₂₅H₂₇N₃O₂S
Molar mass	433.57 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(n1cc2C[C@@H]3C(=C[C@H](CN3C)C(=O)N(CC)CC)c3cccc1c32)c1cccs1

1T-LSD

See also

References