2,3-Bis(acetylmercaptomethyl)quinoxaline is an antiviral agent which can inhibits poliovirus RNA synthesis in vitro and in vivo and inhibits human herpesvirus 1 multiplication in vitro. It does not interfere with attachment, penetration or DNA synthesis, but interrupts a late stage in virus assembly and/or maturation.[1][2]
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Preferred IUPAC name
S,S′-[Quinoxaline-2,3-diylbis(methylene)] di(ethanethioate) | |
Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C14H14N2O2S2 | |
Molar mass | 306.40 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References
edit- ^ Bucchini, Danielle; Girard, Marc (1975–1976). "Inhibition of Herpes Simplex Virus Multiplication by 2,3-Bis(Acetyl Mercaptomethyl)-Quinoxalin". Intervirology. 6 (4–5): 285–95. doi:10.1159/000149482. PMID 186437.
- ^ Mahy, Brian W J (2001). A dictionary of virology (3. ed.). San Diego, Calif. [u.a.]: Academic Press. pp. 2. ISBN 0-12-465327-8.