2-Chloroquinoline is an organic compound with the formula ClC9H6N. It is one of several isomeric chloro derivatives of the bicyclic heterocycle called quinoline. A white solid, 2-chloroquinoline can be prepared from vinylaniline and phosgene.[1] It is a precursor to 2,2'-biquinoline.

2-Chloroquinoline
Names
Preferred IUPAC name
2-Chloroquinoline
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.009.381 Edit this at Wikidata
EC Number
  • 210-317-8
UNII
  • InChI=1S/C9H6ClN/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H
    Key: OFUFXTHGZWIDDB-UHFFFAOYSA-N
  • C1=CC=C2C(=C1)C=CC(=N2)Cl
Properties
C9H6ClN
Molar mass 163.60 g·mol−1
Appearance White solid
Melting point 38 °C (100 °F; 311 K)
Boiling point 266 °C (511 °F; 539 K)
Hazards
GHS labelling:
GHS07: Exclamation mark
Warning
H315, H319, H335
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References

edit
  1. ^ Lee, Byoung Se; Lee, Jae Hak; Chi, Dae Yoon (2002). "Novel Synthesis of 2-Chloroquinolines from 2-Vinylanilines in Nitrile Solvent". Journal of Organic Chemistry. 67 (22): 7884–7886. doi:10.1021/jo016196i. PMID 12398521.