2-Methyltetrahydroquinoline is one of the methyl-substituted derivatives of tetrahydroquinoline. A colorless oil, it is a chiral compound owing to the presence of the methyl substituent. It is produced by the hydrogenation of quinaldine.[1] It is of interest in medicinal chemistry.[2]
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Names | |
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Preferred IUPAC name
2-Methyl-1,2,3,4-tetrahydroquinoline | |
Other names
Tetrahydroquinaldine, 1,2,3,4-Tetrahydroquinaldine
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Identifiers | |
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3D model (JSmol)
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ChEMBL | |
EC Number |
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PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C10H13N | |
Molar mass | 147.221 g·mol−1 |
Appearance | colorless oil |
Boiling point | 125 °C (257 °F; 398 K) (17 Torr) |
Hazards | |
GHS labelling: | |
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Warning | |
H315, H319 | |
P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References
edit- ^ Chakraborty, Sumit; Brennessel, William W.; Jones, William D. (2014). "A Molecular Iron Catalyst for the Acceptorless Dehydrogenation and Hydrogenation of N-Heterocycles". Journal of the American Chemical Society. 136 (24): 8564–8567. doi:10.1021/ja504523b. PMID 24877556.
- ^ Sridharan, Vellaisamy; Suryavanshi, Padmakar A.; Menéndez, J. Carlos (2011). "Advances in the Chemistry of Tetrahydroquinolines". Chemical Reviews. 111 (11): 7157–7259. doi:10.1021/cr100307m. PMID 21830756.