2-dehydro-3-deoxy-D-pentonate aldolase

The enzyme 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) catalyzes the chemical reaction

2-dehydro-3-deoxy-D-pentonate aldolase
Identifiers
EC no.4.1.2.28
CAS no.55326-36-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
2-dehydro-3-deoxy-Dpentonate pyruvate + glycolaldehyde

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase (pyruvate-forming). Other names in common use include 2-keto-3-deoxy-D-pentonate aldolase, 3-deoxy-D-pentulosonic acid aldolase, and 2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase. This enzyme participates in pentose and glucuronate interconversions.

References

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  • Dahms AS (1974). "3-Deoxy-D-pentulosonic acid aldolase and its role in a new pathway of D-xylose degradation". Biochem. Biophys. Res. Commun. 60 (4): 1433–9. doi:10.1016/0006-291X(74)90358-1. PMID 4423285.
  • Dahms AS, Donald A (1982). "2-Keto-3-deoxy-d-xylonate aldolase (3-deoxy-d-pentulosonic acid aldolase)". Carbohydrate Metabolism - Part E. Methods in Enzymology. Vol. 90. pp. 269–72. doi:10.1016/s0076-6879(82)90138-0. ISBN 978-0-12-181990-3. PMID 7154955.