February 7: The Mystics signed Maurita Reid to a training camp contract.
March 29: The Mystics signed Sequoia Holmes and Angel Robinson to training camp contracts.
April 8: The Mystics signed Megan Frazee.
April 8: The Mystics signed Bernice Mosby to a training camp contract.
April 9: The Mystics traded their first-round 2012 draft pick to the Minnesota Lynx in exchange for Nicky Anosike.[1]
April 11: The Mystics traded Lindsey Harding and a second-round pick in the 2012 draft to the Atlanta Dream in exchange for Kelly Miller, draft rights to Ta'Shia Phillips and a first-round pick in the 2012 draft.
April 29: The Mystics traded Katie Smith and Jacinta Monroe to the Seattle Storm in exchange for Jasmine Thomas and a first-round pick in the 2012 draft, and the Indiana Fever's third-round pick in the 2012 draft.
May 2: The Mystics waived Bernice Mosby.
May 17: The Mystics waived Sequoia Holmes and Maurita Reid.
May 28: The Mystics waived Chasity Melvin and Angel Robinson.
May 31: The Mystics waived Ashley Houts and Megan Frazee.
June 9: The Mystics signed Kerri Gardin to an emergency hardship contract.
June 20: The Mystics waived Kerri Gardin.
June 23: The Mystics signed Joy Cheek to an emergency hardship contract.
July 6: The Mystics waived Joy Cheek.
July 7: The Mystics signed Kerri Gardin to an emergency hardship contract.
July 21: The Mystics waived Ta'Shia Phillips and Karima Christmas.