The 2021 Copa Sudamericana final stages was played from 13 July to 20 November 2021.[1] A total of 16 teams competed in the final stages to decide the champions of the 2021 Copa Sudamericana,[2] with the final played in Montevideo, Uruguay at Estadio Centenario.[3]
Starting from the round of 16, the teams are seeded according to their results in the group stage, with the Copa Sudamericana group winners (Pot 1) seeded 1–8, and the Copa Libertadores group third-placed teams (Pot 2) seeded 9–16.
In the round of 16, quarter-finals and semi-finals, each tie is played on a home-and-away two-legged basis, with the higher-seeded team hosting the second leg (Regulations Article 2.2.3). If tied on aggregate, the away goals rule will be used. If still tied, extra time will not be played, and a penalty shoot-out will be used to determine the winners (Regulations Article 2.4.4).
The final is played as a single match at a venue pre-selected by CONMEBOL, with the higher-seeded team designated as the "home" team for administrative purposes (Regulations Article 2.2.6). If tied after regulation, 30 minutes of extra time will be played. If still tied after extra time, a penalty shoot-out will be used to determine the winners (Regulations Article 2.4.5).
The draw for the round of 16 was held on 1 June 2021, 12:00 PYT (UTC−4), at the CONMEBOL Convention Centre in Luque, Paraguay.[4] For the round of 16, the 16 teams were drawn into eight ties (A–H) between a Copa Sudamericana group winner (Pot 1) and a Copa Libertadores group third-placed (Pot 2), with the Copa Sudamericana group winners hosting the second leg. Teams from the same association or the same group could be drawn into the same tie (Regulations Article 2.2.3.2).[2]