2021 Knoxville Challenger

The 2021 Knoxville Challenger was a professional tennis tournament played on indoor hard courts. It was the seventeenth edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Knoxville, United States between 8 and 14 November 2021.

2021 Knoxville Challenger
Date	8–14 November
Edition	17th
Surface	Hard (Indoor)
Location	Knoxville, United States
Champions
Singles
Christopher Eubanks
Doubles
Malek Jaziri / Blaž Rola

Singles main-draw entrants

Seeds

Country	Player	Rank1	Seed
USA	Tennys Sandgren	93	1
GER	Daniel Altmaier	106	2
CAN	Vasek Pospisil	113	3
USA	Mitchell Krueger	148	4
USA	Jack Sock	153	5
USA	J. J. Wolf	159	6
KAZ	Dmitry Popko	171	7
USA	Bjorn Fratangelo	172	8

• ¹ Rankings are as of November 1, 2021.

Other entrants

The following players received wildcards into the singles main draw:

• Aleksandar Kovacevic
• Emilio Nava
• Adam Walton

The following player received entry into the singles main draw using a protected ranking:

• Tatsuma Ito

The following players received entry into the singles main draw as alternates:

• Christian Harrison
• Malek Jaziri
• Peter Polansky

The following players received entry from the qualifying draw:

• JC Aragone
• Gijs Brouwer
• Aidan McHugh
• Donald Young

Champions

Singles

Main article: 2021 Knoxville Challenger – Singles

• Christopher Eubanks def. Daniel Altmaier 6–3, 6–4.

Doubles

Main article: 2021 Knoxville Challenger – Doubles

• Malek Jaziri / Blaž Rola def. Hans Hach Verdugo / Miguel Ángel Reyes-Varela 3–6, 6–3, [10–5].