Diede de Groot and Aniek van Koot defeated the defending champions Yui Kamiji and Jordanne Whiley in the final, 6–1, 6–2 to win the women's doubles wheelchair tennis title at the 2021 US Open.[1]
| Wheelchair women's doubles | |
|---|---|
| 2021 US Open | |
| Champions |  Diede de Groot Aniek van Koot |
| Runners-up |  Yui Kamiji  Jordanne Whiley |
| Score | 6–1, 6–2 |
Seeds
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Diede de Groot / Aniek van Koot (champions)
Yui Kamiji / 
Jordanne Whiley (final)
Draw
editKey
edit- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- SE = Special exempt
- PR = Protected ranking
- ITF = ITF entry
- JE = Junior exempt
- w/o = Walkover
- r = Retired
- d = Defaulted
- SR = Special ranking
Finals
edit| Semifinals | Final | ||||||||||||
| 1 | Diede de Groot Aniek van Koot
| 6 | 6 | ||||||||||
 Dana Mathewson Kgothatso Montjane
| 0 | 2 | |||||||||||
| 1 | Diede de Groot Aniek van Koot
| 6 | 6 | ||||||||||
| 2 | Yui Kamiji Jordanne Whiley
| 1 | 2 | ||||||||||
 Angélica Bernal Momoko Ohtani
| 2 | 0 | |||||||||||
| 2 | Yui Kamiji Jordanne Whiley
| 6 | 6 | ||||||||||