2C-E-FLY

2C-E-FLY
Identifiers
	IUPAC name 2-(8-Ethyl-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b′]difuran-4-yl)ethan-1-amine;
CAS Number	2697190-39-7 ;
PubChem CID	162430105;
CompTox Dashboard (EPA)	DTXSID601342540 ;
Chemical and physical data
Formula	C14H19NO2
Molar mass	233.311 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES NCCc1c2OCCc2c(c2c1CCO2)CC;
	InChI InChI=1S/C14H19NO2/c1-2-9-11-4-7-17-14(11)10(3-6-15)12-5-8-16-13(9)12/h2-8,15H2,1H3; Key:JLKXEQOGLSSESL-UHFFFAOYSA-N;

2C-E-FLY is a recreational designer drug with psychedelic effects. It is slightly less potent than 2C-E or 2C-B-FLY in animal studies but retains drug-appropriate responding.^[1]^[2]^[3]

References

^ Wagmann L, Brandt SD, Stratford A, Maurer HH, Meyer MR (February 2019). "Interactions of phenethylamine-derived psychoactive substances of the 2C-series with human monoamine oxidases". Drug Testing and Analysis. 11 (2): 318–324. doi:10.1002/dta.2494. PMID 30188017. S2CID 52166076.
^ Halberstadt AL, Chatha M, Stratford A, Grill M, Brandt SD (January 2019). "Comparison of the behavioral responses induced by phenylalkylamine hallucinogens and their tetrahydrobenzodifuran ("FLY") and benzodifuran ("DragonFLY") analogs". Neuropharmacology. 144: 368–376. doi:10.1016/j.neuropharm.2018.10.037. PMC 6863604. PMID 30385253.
^ Wagmann L, Hempel N, Richter LH, Brandt SD, Stratford A, Meyer MR (October 2019). "Phenethylamine-derived new psychoactive substances 2C-E-FLY, 2C-EF-FLY, and 2C-T-7-FLY: Investigations on their metabolic fate including isoenzyme activities and their toxicological detectability in urine screenings". Drug Testing and Analysis. 11 (10): 1507–1521. doi:10.1002/dta.2675. PMID 31299701. S2CID 196350806.

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[Wagmann_20191-1] Wagmann L, Brandt SD, Stratford A, Maurer HH, Meyer MR (February 2019). "Interactions of phenethylamine-derived psychoactive substances of the 2C-series with human monoamine oxidases". Drug Testing and Analysis. 11 (2): 318–324. doi:10.1002/dta.2494. PMID 30188017. S2CID 52166076.

[Halberstadt_2019-2] Halberstadt AL, Chatha M, Stratford A, Grill M, Brandt SD (January 2019). "Comparison of the behavioral responses induced by phenylalkylamine hallucinogens and their tetrahydrobenzodifuran ("FLY") and benzodifuran ("DragonFLY") analogs". Neuropharmacology. 144: 368–376. doi:10.1016/j.neuropharm.2018.10.037. PMC 6863604. PMID 30385253.

[Wagmann_2019b-3] Wagmann L, Hempel N, Richter LH, Brandt SD, Stratford A, Meyer MR (October 2019). "Phenethylamine-derived new psychoactive substances 2C-E-FLY, 2C-EF-FLY, and 2C-T-7-FLY: Investigations on their metabolic fate including isoenzyme activities and their toxicological detectability in urine screenings". Drug Testing and Analysis. 11 (10): 1507–1521. doi:10.1002/dta.2675. PMID 31299701. S2CID 196350806.

[1]

[2]

[3]

Identifiers

IUPAC name 2-(8-Ethyl-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b′]difuran-4-yl)ethan-1-amine
CAS Number	2697190-39-7^Y
PubChem CID	162430105
CompTox Dashboard (EPA)	DTXSID601342540
Chemical and physical data
Formula	C₁₄H₁₉NO₂
Molar mass	233.311 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES NCCc1c2OCCc2c(c2c1CCO2)CC
InChI InChI=1S/C14H19NO2/c1-2-9-11-4-7-17-14(11)10(3-6-15)12-5-8-16-13(9)12/h2-8,15H2,1H3 Key:JLKXEQOGLSSESL-UHFFFAOYSA-N

2C-E-FLY

See also

References