4-Fluorobutanol is a chemical compound, a flammable colorless liquid which is a fluorinated alcohol. Like 2-fluoroethanol, it is highly toxic due to its ready metabolism to fluoroacetate.[1][2]
Names | |
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Preferred IUPAC name
4-Fluorobutan-1-ol | |
Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C4H9FO | |
Molar mass | 92.113 g·mol−1 |
Boiling point | 129.3 °C (264.7 °F; 402.4 K) |
miscible | |
Hazards | |
GHS labelling: | |
Warning | |
H226, H315, H319, H335 | |
P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P370+P378, P403+P233, P403+P235, P405, P501 | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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0.9 mg·kg−1(mouse, injected IP or SC) |
Related compounds | |
Related compounds
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1,4-dichlorobutane 1,4-butanediol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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See also
editReferences
edit- ^ Pattison FM (1953). "Toxic Fluorine Compounds". Nature. 172 (4390): 1139–1141. Bibcode:1953Natur.172.1139P. doi:10.1038/1721139a0. PMID 13111268. S2CID 4198735.
- ^ Pattison, F. L. M.; Howell, W. C.; McNamara, A. J.; Schneider, J. C.; Walker, J. F. (1956). "Toxic Fluorine Compounds. III.1 ω-Fluoroalcohols". The Journal of Organic Chemistry. 21 (7): 739–747. doi:10.1021/jo01113a006.