5′′-phosphoribostamycin phosphatase (EC 3.1.3.88) is an enzyme with systematic name 5′′-phosphoribostamycin phosphohydrolase.[1] This enzyme catalyses the following chemical reaction
| 5′′-phosphoribostamycin phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.3.88 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- 5′′-phosphoribostamycin + H2O ribostamycin + phosphate
This enzyme is involved in the biosynthesis of several aminocyclitol antibiotics, including ribostamycin, neomycin and butirosin.
References
edit- ^ Kudo F, Fujii T, Kinoshita S, Eguchi T (July 2007). "Unique O-ribosylation in the biosynthesis of butirosin". Bioorganic & Medicinal Chemistry. 15 (13): 4360–8. doi:10.1016/j.bmc.2007.04.040. PMID 17482823.
External links
edit- 5''-phosphoribostamycin phosphatase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
