5,6-Dihydroxycytosine (Isouramil) can be formed from treatment of DNA with osmium tetroxide.[1]
Names | |
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Preferred IUPAC name
6-Amino-5-hydroxypyrimidine-2,4(1H,3H)-dione | |
Other names
6-Amino-2,4,5-trihydroxypyrimidine
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C4H5N3O3 | |
Molar mass | 143.102 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References
edit- ^ Dizdaroglu, M; Holwitt, E; Hagan, M. P.; Blakely, W. F. (1986). "Formation of cytosine glycol and 5,6-dihydroxycytosine in deoxyribonucleic acid on treatment with osmium tetroxide". The Biochemical Journal. 235 (2): 531–6. doi:10.1042/bj2350531. PMC 1146717. PMID 3741404.