6-O-methylnorlaudanosoline 5'-O-methyltransferase

In enzymology, a 6-O-methylnorlaudanosoline 5'-O-methyltransferase (EC 2.1.1.121) is an enzyme that catalyzes the chemical reaction

6-O-methylnorlaudanosoline 5'-O-methyltransferase
Identifiers
EC no.2.1.1.121
CAS no.89511-99-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline S-adenosyl-L-homocysteine + nororientaline

Thus, the two substrates of this enzyme are S-adenosyl methionine and 6-O-methylnorlaudanosoline, whereas its two products are S-adenosylhomocysteine and nororientaline.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.

References

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  • Rueffer M, Nagakura N, Zenk MH (1983). "A highly specific O-methyltransferase for nororientaline synthesis isolated from Argemone platyceras cell cultures". Planta Med. 49 (12): 196–198. doi:10.1055/s-2007-969849. PMID 17405051.