In enzymology, a 6-aminohexanoate-cyclic-dimer hydrolase (EC 3.5.2.12) is an enzyme that catalyzes the chemical reaction
| 6-aminohexanoate-cyclic-dimer hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.5.2.12 | ||||||||
| CAS no. | 60976-29-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- 1,8-diazacyclotetradecane-2,9-dione + H2O N-(6-aminohexanoyl)-6-aminohexanoate
Thus, the two substrates of this enzyme are 1,8-diazacyclotetradecane-2,9-dione and H2O, whereas its product is N-(6-aminohexanoyl)-6-aminohexanoate.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. The systematic name of this enzyme class is 1,8-diazacyclotetradecane-2,9-dione lactamhydrolase.
References
edit- Kinoshita S, Negoro S, Muramatsu M, Bisaria VS, Sawada S, Okada H (1977). "6-Aminohexanoic acid cyclic dimer hydrolase. A new cyclic amide hydrolase produced by Achromobacter guttatus KI74". Eur. J. Biochem. 80 (2): 489–95. doi:10.1111/j.1432-1033.1977.tb11904.x. PMID 923591.
External links
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